Very Late Relapse of Bilateral Retinoblastoma

Jung Yoon Choi; Hyoung Jin Kang; Ji Won Lee; Hee Young Ju; Che Ry Hong; Hyery Kim; Young Suk Yu; Sung Hye Park; Jung Eun Cheon; Kyung Duk Park; Hee Young Shin

doi:10.1097/MPH.0000000000000310

Very Late Relapse of Bilateral Retinoblastoma

Jung Yoon Choi
, Hyoung Jin Kang
, Ji Won Lee
, Hee Young Ju
, Che Ry Hong
, Hyery Kim
, Young Suk Yu
, Sung Hye Park
, Jung Eun Cheon
, Kyung Duk Park
, Hee Young Shin

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Retinoblastoma usually recurs within the first few years after treatment completion. We report a rare case of very late relapse in a 6-month-old girl who was diagnosed with bilateral retinoblastoma. The patient achieved first remission after treatment with neoadjuvant chemotherapy, enucleation of the right eye, local laser therapy of the left eye, and adjuvant chemotherapy. Extraocular relapse with multiple metastases occurred 13 years and 8 months after treatment. The patient is currently in second complete remission after receiving high-dose chemotherapy and autologous stem cell transplantation. In conclusion, long-term follow-up is needed for early detection of recurrent retinoblastoma.

Original language	English
Pages (from-to)	e264-e267
Journal	Journal of Pediatric Hematology/Oncology
Volume	37
Issue number	4
DOIs	https://doi.org/10.1097/MPH.0000000000000310
State	Published - 1 Dec 2015
Externally published	Yes

Keywords

enucleation
recurrence
retinoblastoma

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/MPH.0000000000000310

Cite this

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title = "Very Late Relapse of Bilateral Retinoblastoma",

abstract = "Retinoblastoma usually recurs within the first few years after treatment completion. We report a rare case of very late relapse in a 6-month-old girl who was diagnosed with bilateral retinoblastoma. The patient achieved first remission after treatment with neoadjuvant chemotherapy, enucleation of the right eye, local laser therapy of the left eye, and adjuvant chemotherapy. Extraocular relapse with multiple metastases occurred 13 years and 8 months after treatment. The patient is currently in second complete remission after receiving high-dose chemotherapy and autologous stem cell transplantation. In conclusion, long-term follow-up is needed for early detection of recurrent retinoblastoma.",

keywords = "enucleation, recurrence, retinoblastoma",

author = "Choi, \{Jung Yoon\} and Kang, \{Hyoung Jin\} and Lee, \{Ji Won\} and Ju, \{Hee Young\} and Hong, \{Che Ry\} and Hyery Kim and Yu, \{Young Suk\} and Park, \{Sung Hye\} and Cheon, \{Jung Eun\} and Park, \{Kyung Duk\} and Shin, \{Hee Young\}",

year = "2015",

month = dec,

day = "1",

doi = "10.1097/MPH.0000000000000310",

language = "English",

volume = "37",

pages = "e264--e267",

journal = "Journal of Pediatric Hematology/Oncology",

issn = "1077-4114",

publisher = "Lippincott Williams and Wilkins",

number = "4",

}

TY - JOUR

T1 - Very Late Relapse of Bilateral Retinoblastoma

AU - Choi, Jung Yoon

AU - Kang, Hyoung Jin

AU - Lee, Ji Won

AU - Ju, Hee Young

AU - Hong, Che Ry

AU - Kim, Hyery

AU - Yu, Young Suk

AU - Park, Sung Hye

AU - Cheon, Jung Eun

AU - Park, Kyung Duk

AU - Shin, Hee Young

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Retinoblastoma usually recurs within the first few years after treatment completion. We report a rare case of very late relapse in a 6-month-old girl who was diagnosed with bilateral retinoblastoma. The patient achieved first remission after treatment with neoadjuvant chemotherapy, enucleation of the right eye, local laser therapy of the left eye, and adjuvant chemotherapy. Extraocular relapse with multiple metastases occurred 13 years and 8 months after treatment. The patient is currently in second complete remission after receiving high-dose chemotherapy and autologous stem cell transplantation. In conclusion, long-term follow-up is needed for early detection of recurrent retinoblastoma.

AB - Retinoblastoma usually recurs within the first few years after treatment completion. We report a rare case of very late relapse in a 6-month-old girl who was diagnosed with bilateral retinoblastoma. The patient achieved first remission after treatment with neoadjuvant chemotherapy, enucleation of the right eye, local laser therapy of the left eye, and adjuvant chemotherapy. Extraocular relapse with multiple metastases occurred 13 years and 8 months after treatment. The patient is currently in second complete remission after receiving high-dose chemotherapy and autologous stem cell transplantation. In conclusion, long-term follow-up is needed for early detection of recurrent retinoblastoma.

KW - enucleation

KW - recurrence

KW - retinoblastoma

UR - https://www.scopus.com/pages/publications/84937965191

U2 - 10.1097/MPH.0000000000000310

DO - 10.1097/MPH.0000000000000310

M3 - Article

C2 - 25757022

AN - SCOPUS:84937965191

SN - 1077-4114

VL - 37

SP - e264-e267

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

IS - 4

ER -

Very Late Relapse of Bilateral Retinoblastoma

Abstract

Keywords

UN SDGs

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