TY - JOUR
T1 - Triterpenes from perilla frutescens var. acuta and their cytotoxic activity
AU - Woo, Kyeong Wan
AU - Han, Ji Young
AU - Choi, Sang Un
AU - Kim, Ki Hyun
AU - Lee, Kang Ro
N1 - Publisher Copyright:
© 2014, Korean Society of Pharmacognosy. All rights reserved.
PY - 2014
Y1 - 2014
N2 - Nine triterpenes were isolated from the petroleum ether and MeOH extract of Perilla frutescens var. acuta leaves. Their structures were determined to be arjunic acid (1), maslinic acid (2), oleanolic acid (3), euscaphic acid (4), tormentic acid (5), 3-O-trans-p-coumaroyltormentic acid (6), 28-formyloxy-3β-hydroxy-urs-12-ene (7), ursolic acid (8), and corosolic acid (9) by spectroscopic methods. The compounds 1, 2, 4, 6, and 7were isolated for the first time from this plant and the Genus Labiatae. The isolated compounds (1-9) were tested for cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro using a Sulforhodamin B bioassay.
AB - Nine triterpenes were isolated from the petroleum ether and MeOH extract of Perilla frutescens var. acuta leaves. Their structures were determined to be arjunic acid (1), maslinic acid (2), oleanolic acid (3), euscaphic acid (4), tormentic acid (5), 3-O-trans-p-coumaroyltormentic acid (6), 28-formyloxy-3β-hydroxy-urs-12-ene (7), ursolic acid (8), and corosolic acid (9) by spectroscopic methods. The compounds 1, 2, 4, 6, and 7were isolated for the first time from this plant and the Genus Labiatae. The isolated compounds (1-9) were tested for cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro using a Sulforhodamin B bioassay.
KW - Cytotoxicity
KW - Labiatae
KW - Perilla frutescens var. acuta
KW - Triterpene
UR - https://www.scopus.com/pages/publications/84908501470
M3 - Article
AN - SCOPUS:84908501470
SN - 1226-3907
VL - 20
SP - 71
EP - 75
JO - Natural Product Sciences
JF - Natural Product Sciences
IS - 2
ER -