Tracheal stenosis depends on the extent of cartilaginous injury in experimental canine model

To test the hypothesis that the development of tracheal stenosis would depend on the extent of tracheal cartilaginous injury, either 90° (n = 6) or 180° (n = 6) of anterior wall of 4 tracheal rings were cauterized in 12 mongrel dogs using Nd-YAG laser. Beginning at 3 weeks after cauterization, 180° tracheal injury resulted in life-threatening tracheal stenosis whereas 90° injury did not. Gross and microscopic examinations showed that after 180° injury, tracheal stenosis was accompanied by the loss of tracheal cartilage and dense fibrosis. These results indicate that tracheal stenosis depends on the extent of tracheal injury in experimental canine model.