Total synthsis of (+)-ambuic acid: α-bromination with 1,2-dibromotetrachloroethane

Sun Hee Jung; Geum Sook Hwang; Sung Il Lee; Do Hyun Ryu

doi:10.1021/jo202357s

Total synthsis of (+)-ambuic acid: α-bromination with 1,2-dibromotetrachloroethane

Sun Hee Jung
, Geum Sook Hwang
, Sung Il Lee
, Do Hyun Ryu

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Total synthesis of (+)-ambuic acid has been accomplished from the readily available stereocontrolled Diels-Alder adduct of cyclopentadiene and iodo-1,4-benzoquinone monoketal through an efficient series of steps. A new method for the highly commendable synthesis of α-brominated Diels-Alder adduct is described.

Original language	English
Pages (from-to)	2513-2518
Number of pages	6
Journal	Journal of Organic Chemistry
Volume	77
Issue number	5
DOIs	https://doi.org/10.1021/jo202357s
State	Published - 2 Mar 2012

Access to Document

10.1021/jo202357s

Cite this

@article{a874647e9dbd4d2f9c4d73ff83015aea,

title = "Total synthsis of (+)-ambuic acid: α-bromination with 1,2-dibromotetrachloroethane",

abstract = "Total synthesis of (+)-ambuic acid has been accomplished from the readily available stereocontrolled Diels-Alder adduct of cyclopentadiene and iodo-1,4-benzoquinone monoketal through an efficient series of steps. A new method for the highly commendable synthesis of α-brominated Diels-Alder adduct is described.",

author = "Jung, \{Sun Hee\} and Hwang, \{Geum Sook\} and Lee, \{Sung Il\} and Ryu, \{Do Hyun\}",

year = "2012",

month = mar,

day = "2",

doi = "10.1021/jo202357s",

language = "English",

volume = "77",

pages = "2513--2518",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "5",

}

TY - JOUR

T1 - Total synthsis of (+)-ambuic acid

T2 - α-bromination with 1,2-dibromotetrachloroethane

AU - Jung, Sun Hee

AU - Hwang, Geum Sook

AU - Lee, Sung Il

AU - Ryu, Do Hyun

PY - 2012/3/2

Y1 - 2012/3/2

N2 - Total synthesis of (+)-ambuic acid has been accomplished from the readily available stereocontrolled Diels-Alder adduct of cyclopentadiene and iodo-1,4-benzoquinone monoketal through an efficient series of steps. A new method for the highly commendable synthesis of α-brominated Diels-Alder adduct is described.

AB - Total synthesis of (+)-ambuic acid has been accomplished from the readily available stereocontrolled Diels-Alder adduct of cyclopentadiene and iodo-1,4-benzoquinone monoketal through an efficient series of steps. A new method for the highly commendable synthesis of α-brominated Diels-Alder adduct is described.

UR - https://www.scopus.com/pages/publications/84863247976

U2 - 10.1021/jo202357s

DO - 10.1021/jo202357s

M3 - Article

C2 - 22280015

AN - SCOPUS:84863247976

SN - 0022-3263

VL - 77

SP - 2513

EP - 2518

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 5

ER -

Total synthsis of (+)-ambuic acid: α-bromination with 1,2-dibromotetrachloroethane

Abstract

Access to Document

Other files and links

Fingerprint

Cite this