Thyroid stimulating hormone and serum, plasma, and platelet brain-derived neurotrophic factor during a 3-month follow-up in patients with major depressive disorder

Ji Hyun Baek; Eun Suk Kang; Maurizio Fava; David Mischoulon; Andrew A. Nierenberg; Dongsoo Lee; Jung Yoon Heo; Hong Jin Jeon

doi:10.1016/j.jad.2014.08.009

Thyroid stimulating hormone and serum, plasma, and platelet brain-derived neurotrophic factor during a 3-month follow-up in patients with major depressive disorder

Ji Hyun Baek
, Eun Suk Kang
, Maurizio Fava
, David Mischoulon
, Andrew A. Nierenberg
, Dongsoo Lee
, Jung Yoon Heo
, Hong Jin Jeon

Department of Psychiatry

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Background Thyroid dysfunction and elevated thyroid stimulating hormone (TSH) are common in patients with depression. TSH might exert its function in the brain through blood levels of brain-derived neurotrophic factor (BDNF). BDNF decreases during depressed states and normalize after treatment. The gap is that the association between TSH and BDNF in patients with major depressive disorder (MDD) is unknown. Methods We studied 105 subjects ¥

Original language	English
Pages (from-to)	112-117
Number of pages	6
Journal	Journal of Affective Disorders
Volume	169
DOIs	https://doi.org/10.1016/j.jad.2014.08.009
State	Published - 1 Dec 2014

Keywords

BDNF
Major depressive disorder
Thyroid hormone
Thyroid-stimulating hormone

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10.1016/j.jad.2014.08.009

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title = "Thyroid stimulating hormone and serum, plasma, and platelet brain-derived neurotrophic factor during a 3-month follow-up in patients with major depressive disorder",

abstract = "Background Thyroid dysfunction and elevated thyroid stimulating hormone (TSH) are common in patients with depression. TSH might exert its function in the brain through blood levels of brain-derived neurotrophic factor (BDNF). BDNF decreases during depressed states and normalize after treatment. The gap is that the association between TSH and BDNF in patients with major depressive disorder (MDD) is unknown. Methods We studied 105 subjects ¥",

keywords = "BDNF, Major depressive disorder, Thyroid hormone, Thyroid-stimulating hormone",

author = "Baek, \{Ji Hyun\} and Kang, \{Eun Suk\} and Maurizio Fava and David Mischoulon and Nierenberg, \{Andrew A.\} and Dongsoo Lee and Heo, \{Jung Yoon\} and Jeon, \{Hong Jin\}",

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doi = "10.1016/j.jad.2014.08.009",

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T1 - Thyroid stimulating hormone and serum, plasma, and platelet brain-derived neurotrophic factor during a 3-month follow-up in patients with major depressive disorder

AU - Baek, Ji Hyun

AU - Kang, Eun Suk

AU - Fava, Maurizio

AU - Mischoulon, David

AU - Nierenberg, Andrew A.

AU - Lee, Dongsoo

AU - Heo, Jung Yoon

AU - Jeon, Hong Jin

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Background Thyroid dysfunction and elevated thyroid stimulating hormone (TSH) are common in patients with depression. TSH might exert its function in the brain through blood levels of brain-derived neurotrophic factor (BDNF). BDNF decreases during depressed states and normalize after treatment. The gap is that the association between TSH and BDNF in patients with major depressive disorder (MDD) is unknown. Methods We studied 105 subjects ¥

AB - Background Thyroid dysfunction and elevated thyroid stimulating hormone (TSH) are common in patients with depression. TSH might exert its function in the brain through blood levels of brain-derived neurotrophic factor (BDNF). BDNF decreases during depressed states and normalize after treatment. The gap is that the association between TSH and BDNF in patients with major depressive disorder (MDD) is unknown. Methods We studied 105 subjects ¥

KW - BDNF

KW - Major depressive disorder

KW - Thyroid hormone

KW - Thyroid-stimulating hormone

UR - https://www.scopus.com/pages/publications/84907352748

U2 - 10.1016/j.jad.2014.08.009

DO - 10.1016/j.jad.2014.08.009

M3 - Article

C2 - 25189990

AN - SCOPUS:84907352748

SN - 0165-0327

VL - 169

SP - 112

EP - 117

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

ER -

Thyroid stimulating hormone and serum, plasma, and platelet brain-derived neurotrophic factor during a 3-month follow-up in patients with major depressive disorder

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Keywords

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