The necessity of chemotherapy in T3N0M0 colon cancer without risk factors

Hae Ran Yun; Hee Cheol Kim; Woo Yong Lee; Yong Beom Cho; Seong Hyeon Yun; Ho Kyung Chun

doi:10.1016/j.amjsurg.2008.09.027

The necessity of chemotherapy in T3N0M0 colon cancer without risk factors

Hae Ran Yun, Hee Cheol Kim, Woo Yong Lee, Yong Beom Cho, Seong Hyeon Yun, Ho Kyung Chun

Department of Surgery

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Background: For patients with T3N0M0 colon cancer without known risk factors, the necessity of chemotherapy has no definite consensus. Methods: From 1994 to 2004, we retrospectively analyzed 247 patients who had pathologically confirmed T3N0M0 colon cancer without risk factors. Results: Among the 247 patients, 198 (80.2%) received chemotherapy and 49 (19.8%) underwent surgery alone. The 5-year survival rate was 92.8% for patients with T3N0M0 colon cancer without risk factors. Only chemotherapy increased survival (P = .032) by multivariate analysis. The 5-year survival rates were 85.4% in the surgery-only group and 94.2% in the group that received surgery with chemotherapy. There was no difference in the therapeutic efficacy of 5-fluorouracil, capecitabine, and uracil/tegafur (P = .424) for survival. Conclusion: The results of this study showed that chemotherapy improved the survival of patients with T3N0M0 colon cancer without risk factors.

Original language	English
Pages (from-to)	354-358
Number of pages	5
Journal	American Journal of Surgery
Volume	198
Issue number	3
DOIs	https://doi.org/10.1016/j.amjsurg.2008.09.027
State	Published - Sep 2009

Keywords

Chemotherapy
Risk factors
T3N0M0 colon cancer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.amjsurg.2008.09.027

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@article{0c1650b5db5549afa200b65d2f0ca086,

title = "The necessity of chemotherapy in T3N0M0 colon cancer without risk factors",

abstract = "Background: For patients with T3N0M0 colon cancer without known risk factors, the necessity of chemotherapy has no definite consensus. Methods: From 1994 to 2004, we retrospectively analyzed 247 patients who had pathologically confirmed T3N0M0 colon cancer without risk factors. Results: Among the 247 patients, 198 (80.2\%) received chemotherapy and 49 (19.8\%) underwent surgery alone. The 5-year survival rate was 92.8\% for patients with T3N0M0 colon cancer without risk factors. Only chemotherapy increased survival (P = .032) by multivariate analysis. The 5-year survival rates were 85.4\% in the surgery-only group and 94.2\% in the group that received surgery with chemotherapy. There was no difference in the therapeutic efficacy of 5-fluorouracil, capecitabine, and uracil/tegafur (P = .424) for survival. Conclusion: The results of this study showed that chemotherapy improved the survival of patients with T3N0M0 colon cancer without risk factors.",

keywords = "Chemotherapy, Risk factors, T3N0M0 colon cancer",

author = "Yun, \{Hae Ran\} and Kim, \{Hee Cheol\} and Lee, \{Woo Yong\} and Cho, \{Yong Beom\} and Yun, \{Seong Hyeon\} and Chun, \{Ho Kyung\}",

year = "2009",

month = sep,

doi = "10.1016/j.amjsurg.2008.09.027",

language = "English",

volume = "198",

pages = "354--358",

journal = "American Journal of Surgery",

issn = "0002-9610",

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number = "3",

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TY - JOUR

T1 - The necessity of chemotherapy in T3N0M0 colon cancer without risk factors

AU - Yun, Hae Ran

AU - Kim, Hee Cheol

AU - Lee, Woo Yong

AU - Cho, Yong Beom

AU - Yun, Seong Hyeon

AU - Chun, Ho Kyung

PY - 2009/9

Y1 - 2009/9

N2 - Background: For patients with T3N0M0 colon cancer without known risk factors, the necessity of chemotherapy has no definite consensus. Methods: From 1994 to 2004, we retrospectively analyzed 247 patients who had pathologically confirmed T3N0M0 colon cancer without risk factors. Results: Among the 247 patients, 198 (80.2%) received chemotherapy and 49 (19.8%) underwent surgery alone. The 5-year survival rate was 92.8% for patients with T3N0M0 colon cancer without risk factors. Only chemotherapy increased survival (P = .032) by multivariate analysis. The 5-year survival rates were 85.4% in the surgery-only group and 94.2% in the group that received surgery with chemotherapy. There was no difference in the therapeutic efficacy of 5-fluorouracil, capecitabine, and uracil/tegafur (P = .424) for survival. Conclusion: The results of this study showed that chemotherapy improved the survival of patients with T3N0M0 colon cancer without risk factors.

AB - Background: For patients with T3N0M0 colon cancer without known risk factors, the necessity of chemotherapy has no definite consensus. Methods: From 1994 to 2004, we retrospectively analyzed 247 patients who had pathologically confirmed T3N0M0 colon cancer without risk factors. Results: Among the 247 patients, 198 (80.2%) received chemotherapy and 49 (19.8%) underwent surgery alone. The 5-year survival rate was 92.8% for patients with T3N0M0 colon cancer without risk factors. Only chemotherapy increased survival (P = .032) by multivariate analysis. The 5-year survival rates were 85.4% in the surgery-only group and 94.2% in the group that received surgery with chemotherapy. There was no difference in the therapeutic efficacy of 5-fluorouracil, capecitabine, and uracil/tegafur (P = .424) for survival. Conclusion: The results of this study showed that chemotherapy improved the survival of patients with T3N0M0 colon cancer without risk factors.

KW - Chemotherapy

KW - Risk factors

KW - T3N0M0 colon cancer

UR - https://www.scopus.com/pages/publications/69349105009

U2 - 10.1016/j.amjsurg.2008.09.027

DO - 10.1016/j.amjsurg.2008.09.027

M3 - Article

C2 - 19716883

AN - SCOPUS:69349105009

SN - 0002-9610

VL - 198

SP - 354

EP - 358

JO - American Journal of Surgery

JF - American Journal of Surgery

IS - 3

ER -

The necessity of chemotherapy in T3N0M0 colon cancer without risk factors

Abstract

Keywords

UN SDGs

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