Synthesis of optically active O-protected (S)- and (R)-3-hydroxyaldehydes

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Abstract

(S)-3-Formyloxyaldehydes, chiral synthons for natural product synthesis were synthesized via highly stereoselective hydrogenation of the unsaturated furanose ring system derived from D-glucose or D-xylose. Alternatively, (R)-3-formyloxyaldehydes were prepared via deoxygenation of 3-hydroxyfuranoses derived from D-glucose or D-xylose.

Original languageEnglish
Pages (from-to)367-370
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number3
DOIs
StatePublished - 14 Jan 1991

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