Surface modification technology for bio-MEMS

Dong Sik Shin, Chan Ku Kang, Jae Kwon Kim, Woo Jae Chung, Ki Hoon Jang, Yoon Sik Lee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

We have modified the surfaces of glass and stainless steel with polymers. The purposes of surface modification are for effective protein immobilization and increasing biocompatibility. The surface modified substrates were characterized by contact angle measurement, atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), and confocal fluorescence microscopy. Protein adsorption test was performed on the modified surfaces via enzyme-substrate reaction and fluorescence intensity measurement. We observed a drastic decrease of nonspecific adsorption of proteins when the surfaces are modified with hydrophilic polymers.

Original languageEnglish
Title of host publicationTRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1746-1749
Number of pages4
ISBN (Electronic)0780377311, 9780780377318
DOIs
StatePublished - 2003
Externally publishedYes
Event12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers - Boston, United States
Duration: 8 Jun 200312 Jun 2003

Publication series

NameTRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers
Volume2

Conference

Conference12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers
Country/TerritoryUnited States
CityBoston
Period8/06/0312/06/03

Keywords

  • Atomic force microscopy
  • Atomic measurements
  • Fluorescence
  • Force measurement
  • Glass
  • Goniometers
  • Photoelectron microscopy
  • Polymers
  • Proteins
  • Steel

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