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Surface enhanced Raman scattering based molecule detection using self-assembled DNA nanostructures

  • Myoungsoon Kim
  • , Junwye Lee
  • , Sreekantha Reddy Dugasani
  • , Nam Huh
  • , Sung Ha Park
  • , Sang Chul Park
  • Samsung
  • Sungkyunkwan University

Research output: Contribution to journalArticlepeer-review

Abstract

A novel method of Surface Enhanced Raman Scattering (SERS) based molecular detection was developed using self-assembled DNA nanostructures. Molecule detection using rigid, shape-controllable DNA nanostructures provides significant advantages such as accurate control of the particle distance and geometrical programmability of the DNA nanostructure. We successfully detected the Cy3 dye, a Raman-active molecule, at 1461, 1590, and 1619 cm-1 using a Ag-enhanced Au-DNA nanostructure. Consequently, DNA-guided SERS detection is expected to contribute significantly to molecular detecting systems in the near future.

Original languageEnglish
Pages (from-to)1032-1035
Number of pages4
JournalCurrent Applied Physics
Volume15
Issue number9
DOIs
StatePublished - 29 Jun 2015
Externally publishedYes

Keywords

  • Cy3
  • DNA nanotechnology
  • Gold nanoparticle
  • Self-assembly
  • Surface enhanced Raman scattering

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