Abstract
A novel method of Surface Enhanced Raman Scattering (SERS) based molecular detection was developed using self-assembled DNA nanostructures. Molecule detection using rigid, shape-controllable DNA nanostructures provides significant advantages such as accurate control of the particle distance and geometrical programmability of the DNA nanostructure. We successfully detected the Cy3 dye, a Raman-active molecule, at 1461, 1590, and 1619 cm-1 using a Ag-enhanced Au-DNA nanostructure. Consequently, DNA-guided SERS detection is expected to contribute significantly to molecular detecting systems in the near future.
| Original language | English |
|---|---|
| Pages (from-to) | 1032-1035 |
| Number of pages | 4 |
| Journal | Current Applied Physics |
| Volume | 15 |
| Issue number | 9 |
| DOIs | |
| State | Published - 29 Jun 2015 |
| Externally published | Yes |
Keywords
- Cy3
- DNA nanotechnology
- Gold nanoparticle
- Self-assembly
- Surface enhanced Raman scattering