Substituent effects of phenylboronic acid-functionalized resins in pH-controlled separation of catecholic flavonoids

Sang Min Lee; Jinhyo Chung; Mi Sic Gong; Bong Hyun Jun; Dae Hyuk Kweon; Woo Jae Chung

doi:10.1016/j.jiec.2019.04.031

Substituent effects of phenylboronic acid-functionalized resins in pH-controlled separation of catecholic flavonoids

Sang Min Lee, Jinhyo Chung, Mi Sic Gong, Bong Hyun Jun, Dae Hyuk Kweon, Woo Jae Chung

Department of Integrative Biotechnology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Gel resins modified with different phenylboronic acid derivatives were prepared for selective separation of catechol-containing flavonoids. The phenylboronic acid gel (PBA-gel) resins showed pH-dependent adsorption and release of catechol-containing flavonoid quercetin. Under optimal pH control, the PBA-gel resins exhibited high quercetin binding capacity of up to 120 mg/g of resin and demonstrate quantitative release of the specifically bound quercetin. In addition, the recyclability of PBA-gel resin was confirmed by repeated binding and hydrolysis of quercetin with no significant loss of capacity during at least five cycles, showing great potential of PBA-gels as practical tools for selective separation of catechol-containing flavonoids.

Original language	English
Pages (from-to)	164-170
Number of pages	7
Journal	Journal of Industrial and Engineering Chemistry
Volume	77
DOIs	https://doi.org/10.1016/j.jiec.2019.04.031
State	Published - 25 Sep 2019

Keywords

Flavonoid
pH-controlled separation
Phenylboronic acid
Quercetin
Solid-supported reagent

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10.1016/j.jiec.2019.04.031

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title = "Substituent effects of phenylboronic acid-functionalized resins in pH-controlled separation of catecholic flavonoids",

abstract = "Gel resins modified with different phenylboronic acid derivatives were prepared for selective separation of catechol-containing flavonoids. The phenylboronic acid gel (PBA-gel) resins showed pH-dependent adsorption and release of catechol-containing flavonoid quercetin. Under optimal pH control, the PBA-gel resins exhibited high quercetin binding capacity of up to 120 mg/g of resin and demonstrate quantitative release of the specifically bound quercetin. In addition, the recyclability of PBA-gel resin was confirmed by repeated binding and hydrolysis of quercetin with no significant loss of capacity during at least five cycles, showing great potential of PBA-gels as practical tools for selective separation of catechol-containing flavonoids.",

keywords = "Flavonoid, pH-controlled separation, Phenylboronic acid, Quercetin, Solid-supported reagent",

author = "Lee, \{Sang Min\} and Jinhyo Chung and Gong, \{Mi Sic\} and Jun, \{Bong Hyun\} and Kweon, \{Dae Hyuk\} and Chung, \{Woo Jae\}",

note = "Publisher Copyright: {\textcopyright} 2019 The Korean Society of Industrial and Engineering Chemistry",

year = "2019",

month = sep,

day = "25",

doi = "10.1016/j.jiec.2019.04.031",

language = "English",

volume = "77",

pages = "164--170",

journal = "Journal of Industrial and Engineering Chemistry",

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publisher = "Korean Society of Industrial Engineering Chemistry",

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TY - JOUR

T1 - Substituent effects of phenylboronic acid-functionalized resins in pH-controlled separation of catecholic flavonoids

AU - Lee, Sang Min

AU - Chung, Jinhyo

AU - Gong, Mi Sic

AU - Jun, Bong Hyun

AU - Kweon, Dae Hyuk

AU - Chung, Woo Jae

PY - 2019/9/25

Y1 - 2019/9/25

N2 - Gel resins modified with different phenylboronic acid derivatives were prepared for selective separation of catechol-containing flavonoids. The phenylboronic acid gel (PBA-gel) resins showed pH-dependent adsorption and release of catechol-containing flavonoid quercetin. Under optimal pH control, the PBA-gel resins exhibited high quercetin binding capacity of up to 120 mg/g of resin and demonstrate quantitative release of the specifically bound quercetin. In addition, the recyclability of PBA-gel resin was confirmed by repeated binding and hydrolysis of quercetin with no significant loss of capacity during at least five cycles, showing great potential of PBA-gels as practical tools for selective separation of catechol-containing flavonoids.

AB - Gel resins modified with different phenylboronic acid derivatives were prepared for selective separation of catechol-containing flavonoids. The phenylboronic acid gel (PBA-gel) resins showed pH-dependent adsorption and release of catechol-containing flavonoid quercetin. Under optimal pH control, the PBA-gel resins exhibited high quercetin binding capacity of up to 120 mg/g of resin and demonstrate quantitative release of the specifically bound quercetin. In addition, the recyclability of PBA-gel resin was confirmed by repeated binding and hydrolysis of quercetin with no significant loss of capacity during at least five cycles, showing great potential of PBA-gels as practical tools for selective separation of catechol-containing flavonoids.

KW - Flavonoid

KW - pH-controlled separation

KW - Phenylboronic acid

KW - Quercetin

KW - Solid-supported reagent

UR - https://www.scopus.com/pages/publications/85065444912

U2 - 10.1016/j.jiec.2019.04.031

DO - 10.1016/j.jiec.2019.04.031

M3 - Article

AN - SCOPUS:85065444912

SN - 1226-086X

VL - 77

SP - 164

EP - 170

JO - Journal of Industrial and Engineering Chemistry

JF - Journal of Industrial and Engineering Chemistry

ER -

Substituent effects of phenylboronic acid-functionalized resins in pH-controlled separation of catecholic flavonoids

Abstract

Keywords

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