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Structure-guided design and synthesis of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi

  • Patrick A. Dome
  • , Pyeonghwa Jeong
  • , Gibeom Nam
  • , Hongjun Jang
  • , Angela Rivera
  • , Anna Floyd Averette
  • , Eunchong Park
  • , Tzu Chieh Liao
  • , Maria Ciofani
  • , Jianli Wu
  • , Jen Tsan Ashley Chi
  • , Ronald A. Venters
  • , Hyun Ju Park
  • , William J. Steinbach
  • , Praveen R. Juvvadi
  • , Joseph Heitman
  • , Jiyong Hong

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Medicine and Dentistry