Stereoselective syntheses of (±)-epibatidine analogues

Yong Hyun Kim; Do Youn Won; Chang Young Oh; Kee Young Lee; Yiu Suk Lee; Nam Tae Woo; Young Ho Park; Hyun Ju Park; Won Hun Ham

doi:10.1007/BF02975259

Stereoselective syntheses of (±)-epibatidine analogues

Yong Hyun Kim
, Do Youn Won
, Chang Young Oh
, Kee Young Lee
, Yiu Suk Lee
, Nam Tae Woo
, Young Ho Park
, Hyun Ju Park
, Won Hun Ham

Amorepacific Corporation
Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Stereoselective syntheses of (±)-epibatidine analogues 2, which contain the 8-azabicyclo [3.2.1]octane ring system, were achieved by using palladium-catalyzed cross-coupling reaction from 4 and the analgesic activity was tested by Mouse writhing antinociceptive assay.

Original language	English
Pages (from-to)	45-48
Number of pages	4
Journal	Archives of Pharmacal Research
Volume	25
Issue number	1
DOIs	https://doi.org/10.1007/BF02975259
State	Published - 28 Feb 2002
Externally published	Yes

Keywords

Alkaloids
Analgesics
Epibatidine
Palladium
Stereocontrol

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10.1007/BF02975259

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title = "Stereoselective syntheses of (±)-epibatidine analogues",

abstract = "Stereoselective syntheses of (±)-epibatidine analogues 2, which contain the 8-azabicyclo [3.2.1]octane ring system, were achieved by using palladium-catalyzed cross-coupling reaction from 4 and the analgesic activity was tested by Mouse writhing antinociceptive assay.",

keywords = "Alkaloids, Analgesics, Epibatidine, Palladium, Stereocontrol",

author = "Kim, \{Yong Hyun\} and Won, \{Do Youn\} and Oh, \{Chang Young\} and Lee, \{Kee Young\} and Lee, \{Yiu Suk\} and Woo, \{Nam Tae\} and Park, \{Young Ho\} and Park, \{Hyun Ju\} and Ham, \{Won Hun\}",

year = "2002",

month = feb,

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doi = "10.1007/BF02975259",

language = "English",

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journal = "Archives of Pharmacal Research",

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T1 - Stereoselective syntheses of (±)-epibatidine analogues

AU - Kim, Yong Hyun

AU - Won, Do Youn

AU - Oh, Chang Young

AU - Lee, Kee Young

AU - Lee, Yiu Suk

AU - Woo, Nam Tae

AU - Park, Young Ho

AU - Park, Hyun Ju

AU - Ham, Won Hun

PY - 2002/2/28

Y1 - 2002/2/28

N2 - Stereoselective syntheses of (±)-epibatidine analogues 2, which contain the 8-azabicyclo [3.2.1]octane ring system, were achieved by using palladium-catalyzed cross-coupling reaction from 4 and the analgesic activity was tested by Mouse writhing antinociceptive assay.

AB - Stereoselective syntheses of (±)-epibatidine analogues 2, which contain the 8-azabicyclo [3.2.1]octane ring system, were achieved by using palladium-catalyzed cross-coupling reaction from 4 and the analgesic activity was tested by Mouse writhing antinociceptive assay.

KW - Alkaloids

KW - Analgesics

KW - Epibatidine

KW - Palladium

KW - Stereocontrol

UR - https://www.scopus.com/pages/publications/0036484756

U2 - 10.1007/BF02975259

DO - 10.1007/BF02975259

M3 - Article

C2 - 11885690

AN - SCOPUS:0036484756

SN - 0253-6269

VL - 25

SP - 45

EP - 48

JO - Archives of Pharmacal Research

JF - Archives of Pharmacal Research

IS - 1

ER -

Stereoselective syntheses of (±)-epibatidine analogues

Abstract

Keywords

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