Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267

James M. Aramini; Donald Petrey; Dong Yup Lee; Haleema Janjua; Rong Xiao; Thomas B. Acton; John K. Everett; Gaetano T. Montelione

doi:10.1007/s10969-012-9135-5

Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267

James M. Aramini
, Donald Petrey
, Dong Yup Lee
, Haleema Janjua
, Rong Xiao
, Thomas B. Acton
, John K. Everett
, Gaetano T. Montelione

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Protein domain family PF11267 (DUF3067) is a family of proteins of unknown function found in both bacteria and eukaryotes. Here we present the solution NMR structure of the 102-residue Alr2454 protein from Nostoc sp. PCC 7120, which constitutes the first structural representative from this conserved protein domain family. The structure of Nostoc sp. Alr2454 adopts a novel protein fold.

Original language	English
Pages (from-to)	171-176
Number of pages	6
Journal	Journal of Structural and Functional Genomics
Volume	13
Issue number	3
DOIs	https://doi.org/10.1007/s10969-012-9135-5
State	Published - Sep 2012
Externally published	Yes

Keywords

Alr2454 protein
DUF3067
PF11267
Protein Structure Initiative
Solution NMR structure
Structural genomics

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10.1007/s10969-012-9135-5

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title = "Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267",

abstract = "Protein domain family PF11267 (DUF3067) is a family of proteins of unknown function found in both bacteria and eukaryotes. Here we present the solution NMR structure of the 102-residue Alr2454 protein from Nostoc sp. PCC 7120, which constitutes the first structural representative from this conserved protein domain family. The structure of Nostoc sp. Alr2454 adopts a novel protein fold.",

keywords = "Alr2454 protein, DUF3067, PF11267, Protein Structure Initiative, Solution NMR structure, Structural genomics",

author = "Aramini, \{James M.\} and Donald Petrey and Lee, \{Dong Yup\} and Haleema Janjua and Rong Xiao and Acton, \{Thomas B.\} and Everett, \{John K.\} and Montelione, \{Gaetano T.\}",

year = "2012",

month = sep,

doi = "10.1007/s10969-012-9135-5",

language = "English",

volume = "13",

pages = "171--176",

journal = "Journal of Structural and Functional Genomics",

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publisher = "Springer Netherlands",

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TY - JOUR

T1 - Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267

AU - Aramini, James M.

AU - Petrey, Donald

AU - Lee, Dong Yup

AU - Janjua, Haleema

AU - Xiao, Rong

AU - Acton, Thomas B.

AU - Everett, John K.

AU - Montelione, Gaetano T.

PY - 2012/9

Y1 - 2012/9

N2 - Protein domain family PF11267 (DUF3067) is a family of proteins of unknown function found in both bacteria and eukaryotes. Here we present the solution NMR structure of the 102-residue Alr2454 protein from Nostoc sp. PCC 7120, which constitutes the first structural representative from this conserved protein domain family. The structure of Nostoc sp. Alr2454 adopts a novel protein fold.

AB - Protein domain family PF11267 (DUF3067) is a family of proteins of unknown function found in both bacteria and eukaryotes. Here we present the solution NMR structure of the 102-residue Alr2454 protein from Nostoc sp. PCC 7120, which constitutes the first structural representative from this conserved protein domain family. The structure of Nostoc sp. Alr2454 adopts a novel protein fold.

KW - Alr2454 protein

KW - DUF3067

KW - PF11267

KW - Protein Structure Initiative

KW - Solution NMR structure

KW - Structural genomics

UR - https://www.scopus.com/pages/publications/84865498162

U2 - 10.1007/s10969-012-9135-5

DO - 10.1007/s10969-012-9135-5

M3 - Article

C2 - 22592539

AN - SCOPUS:84865498162

SN - 1345-711X

VL - 13

SP - 171

EP - 176

JO - Journal of Structural and Functional Genomics

JF - Journal of Structural and Functional Genomics

IS - 3

ER -

Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267

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Keywords

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