Selective and sensitive determination of dopamine by composites of polypyrrole and graphene modified electrodes

Peng Si; Hailan Chen; Palanisamy Kannan; Dong Hwan Kim

doi:10.1039/c1an15772h

Selective and sensitive determination of dopamine by composites of polypyrrole and graphene modified electrodes

Peng Si, Hailan Chen, Palanisamy Kannan, Dong Hwan Kim

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

116 Scopus citations

Abstract

A novel method is developed to fabricate the polypyrrole (PPy) and graphene thin films on electrodes by electrochemical polymerization of pyrrole with graphene oxide (GO) as a dopant, followed by electrochemical reduction of GO in the composite film. The composite of PPy and electrochemically reduced graphene oxide (eRGO)-modified electrode is highly sensitive and selective toward the detection of dopamine (DA) in the presence of high concentrations of ascorbic acid (AA) and uric acid (UA). The sensing performance of the PPy/eRGO-modified electrode is investigated by differential pulse voltammetry (DPV), revealing a linear range of 0.1-150 μM with a detection limit of 23 nM (S/N = 3). The practical application of the PPy/eRGO-modified electrode is successfully demonstrated for DA determination in human blood serum.

Original language	English
Pages (from-to)	5134-5138
Number of pages	5
Journal	Analyst
Volume	136
Issue number	24
DOIs	https://doi.org/10.1039/c1an15772h
State	Published - 21 Dec 2011
Externally published	Yes

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title = "Selective and sensitive determination of dopamine by composites of polypyrrole and graphene modified electrodes",

abstract = "A novel method is developed to fabricate the polypyrrole (PPy) and graphene thin films on electrodes by electrochemical polymerization of pyrrole with graphene oxide (GO) as a dopant, followed by electrochemical reduction of GO in the composite film. The composite of PPy and electrochemically reduced graphene oxide (eRGO)-modified electrode is highly sensitive and selective toward the detection of dopamine (DA) in the presence of high concentrations of ascorbic acid (AA) and uric acid (UA). The sensing performance of the PPy/eRGO-modified electrode is investigated by differential pulse voltammetry (DPV), revealing a linear range of 0.1-150 μM with a detection limit of 23 nM (S/N = 3). The practical application of the PPy/eRGO-modified electrode is successfully demonstrated for DA determination in human blood serum.",

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T1 - Selective and sensitive determination of dopamine by composites of polypyrrole and graphene modified electrodes

AU - Si, Peng

AU - Chen, Hailan

AU - Kannan, Palanisamy

AU - Kim, Dong Hwan

PY - 2011/12/21

Y1 - 2011/12/21

N2 - A novel method is developed to fabricate the polypyrrole (PPy) and graphene thin films on electrodes by electrochemical polymerization of pyrrole with graphene oxide (GO) as a dopant, followed by electrochemical reduction of GO in the composite film. The composite of PPy and electrochemically reduced graphene oxide (eRGO)-modified electrode is highly sensitive and selective toward the detection of dopamine (DA) in the presence of high concentrations of ascorbic acid (AA) and uric acid (UA). The sensing performance of the PPy/eRGO-modified electrode is investigated by differential pulse voltammetry (DPV), revealing a linear range of 0.1-150 μM with a detection limit of 23 nM (S/N = 3). The practical application of the PPy/eRGO-modified electrode is successfully demonstrated for DA determination in human blood serum.

AB - A novel method is developed to fabricate the polypyrrole (PPy) and graphene thin films on electrodes by electrochemical polymerization of pyrrole with graphene oxide (GO) as a dopant, followed by electrochemical reduction of GO in the composite film. The composite of PPy and electrochemically reduced graphene oxide (eRGO)-modified electrode is highly sensitive and selective toward the detection of dopamine (DA) in the presence of high concentrations of ascorbic acid (AA) and uric acid (UA). The sensing performance of the PPy/eRGO-modified electrode is investigated by differential pulse voltammetry (DPV), revealing a linear range of 0.1-150 μM with a detection limit of 23 nM (S/N = 3). The practical application of the PPy/eRGO-modified electrode is successfully demonstrated for DA determination in human blood serum.

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U2 - 10.1039/c1an15772h

DO - 10.1039/c1an15772h

M3 - Article

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SN - 0003-2654

VL - 136

SP - 5134

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JO - Analyst

JF - Analyst

IS - 24

ER -

Selective and sensitive determination of dopamine by composites of polypyrrole and graphene modified electrodes

Abstract

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