Rhodium(III)-catalyzed selective C-H cyanation of indolines and indoles with an easily accessible cyano source

Neeraj Kumar Mishra; Taejoo Jeong; Satyasheel Sharma; Youngmi Shin; Sangil Han; Jihye Park; Joa Sub Oh; Jong Hwan Kwak; Young Hoon Jung; In Su Kim

doi:10.1002/adsc.201401152

Rhodium(III)-catalyzed selective C-H cyanation of indolines and indoles with an easily accessible cyano source

Neeraj Kumar Mishra
, Taejoo Jeong
, Satyasheel Sharma
, Youngmi Shin
, Sangil Han
, Jihye Park
, Joa Sub Oh
, Jong Hwan Kwak
, Young Hoon Jung
, In Su Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

95 Scopus citations

Abstract

The rhodium-catalyzed selective cyanation of C-H bonds of indolines and indoles with N-cyano-N-phenyl-para-methylbenzenesulfonamide is described. This protocol offers a facile access to C-7 cyanated indolines and C-2 cyanated indoles with high site selectivity and excellent functional group tolerance.

Original language	English
Pages (from-to)	1293-1298
Number of pages	6
Journal	Advanced Synthesis and Catalysis
Volume	357
Issue number	6
DOIs	https://doi.org/10.1002/adsc.201401152
State	Published - 13 Apr 2015

Keywords

C-H activation
cyanation
indoles
indolines
rhodium

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10.1002/adsc.201401152

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title = "Rhodium(III)-catalyzed selective C-H cyanation of indolines and indoles with an easily accessible cyano source",

abstract = "The rhodium-catalyzed selective cyanation of C-H bonds of indolines and indoles with N-cyano-N-phenyl-para-methylbenzenesulfonamide is described. This protocol offers a facile access to C-7 cyanated indolines and C-2 cyanated indoles with high site selectivity and excellent functional group tolerance.",

keywords = "C-H activation, cyanation, indoles, indolines, rhodium",

author = "Mishra, \{Neeraj Kumar\} and Taejoo Jeong and Satyasheel Sharma and Youngmi Shin and Sangil Han and Jihye Park and Oh, \{Joa Sub\} and Kwak, \{Jong Hwan\} and Jung, \{Young Hoon\} and Kim, \{In Su\}",

note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim.",

year = "2015",

month = apr,

day = "13",

doi = "10.1002/adsc.201401152",

language = "English",

volume = "357",

pages = "1293--1298",

journal = "Advanced Synthesis and Catalysis",

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TY - JOUR

T1 - Rhodium(III)-catalyzed selective C-H cyanation of indolines and indoles with an easily accessible cyano source

AU - Mishra, Neeraj Kumar

AU - Jeong, Taejoo

AU - Sharma, Satyasheel

AU - Shin, Youngmi

AU - Han, Sangil

AU - Park, Jihye

AU - Oh, Joa Sub

AU - Kwak, Jong Hwan

AU - Jung, Young Hoon

AU - Kim, In Su

PY - 2015/4/13

Y1 - 2015/4/13

N2 - The rhodium-catalyzed selective cyanation of C-H bonds of indolines and indoles with N-cyano-N-phenyl-para-methylbenzenesulfonamide is described. This protocol offers a facile access to C-7 cyanated indolines and C-2 cyanated indoles with high site selectivity and excellent functional group tolerance.

AB - The rhodium-catalyzed selective cyanation of C-H bonds of indolines and indoles with N-cyano-N-phenyl-para-methylbenzenesulfonamide is described. This protocol offers a facile access to C-7 cyanated indolines and C-2 cyanated indoles with high site selectivity and excellent functional group tolerance.

KW - C-H activation

KW - cyanation

KW - indoles

KW - indolines

KW - rhodium

UR - https://www.scopus.com/pages/publications/84926621594

U2 - 10.1002/adsc.201401152

DO - 10.1002/adsc.201401152

M3 - Article

AN - SCOPUS:84926621594

SN - 1615-4150

VL - 357

SP - 1293

EP - 1298

JO - Advanced Synthesis and Catalysis

JF - Advanced Synthesis and Catalysis

IS - 6

ER -

Rhodium(III)-catalyzed selective C-H cyanation of indolines and indoles with an easily accessible cyano source

Abstract

Keywords

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