Rh(III)-catalyzed C-H alkylation of 2-arylbenzothiazoles with α-diazo esters

Miji Choi; Jihye Park; Neeraj Kumar Mishra; Seok Yong Lee; Jun Hyeong Kim; Kyung Min Jeong; Jeongmi Lee; Young Hoon Jung; In Su Kim

doi:10.1016/j.tetlet.2015.06.036

Rh(III)-catalyzed C-H alkylation of 2-arylbenzothiazoles with α-diazo esters

Miji Choi
, Jihye Park
, Neeraj Kumar Mishra
, Seok Yong Lee
, Jun Hyeong Kim
, Kyung Min Jeong
, Jeongmi Lee
, Young Hoon Jung
, In Su Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Abstract The rhodium(III)-catalyzed ortho-C-H functionalization of 2-arylbenzo[d]thiazoles with α-diazo esters is described. This transformation provides the facile and efficient construction of C2-alkylated 2-arylbenzo[d]thiazoles in the absence of external oxidants, and releases benign N₂ gas as the only byproduct.

Original language	English
Article number	46428
Pages (from-to)	4678-4682
Number of pages	5
Journal	Tetrahedron Letters
Volume	56
Issue number	32
DOIs	https://doi.org/10.1016/j.tetlet.2015.06.036
State	Published - 14 Jul 2015

Keywords

2-Arylbenzothiazole
Alkylation
C-H activation
Diazo ester
Rhodium

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10.1016/j.tetlet.2015.06.036

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@article{d794344c5d1b4465bb282db3c40001b1,

title = "Rh(III)-catalyzed C-H alkylation of 2-arylbenzothiazoles with α-diazo esters",

abstract = "Abstract The rhodium(III)-catalyzed ortho-C-H functionalization of 2-arylbenzo[d]thiazoles with α-diazo esters is described. This transformation provides the facile and efficient construction of C2-alkylated 2-arylbenzo[d]thiazoles in the absence of external oxidants, and releases benign N2 gas as the only byproduct.",

keywords = "2-Arylbenzothiazole, Alkylation, C-H activation, Diazo ester, Rhodium",

author = "Miji Choi and Jihye Park and Mishra, \{Neeraj Kumar\} and Lee, \{Seok Yong\} and Kim, \{Jun Hyeong\} and Jeong, \{Kyung Min\} and Jeongmi Lee and Jung, \{Young Hoon\} and Kim, \{In Su\}",

year = "2015",

month = jul,

day = "14",

doi = "10.1016/j.tetlet.2015.06.036",

language = "English",

volume = "56",

pages = "4678--4682",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "32",

}

TY - JOUR

T1 - Rh(III)-catalyzed C-H alkylation of 2-arylbenzothiazoles with α-diazo esters

AU - Choi, Miji

AU - Park, Jihye

AU - Mishra, Neeraj Kumar

AU - Lee, Seok Yong

AU - Kim, Jun Hyeong

AU - Jeong, Kyung Min

AU - Lee, Jeongmi

AU - Jung, Young Hoon

AU - Kim, In Su

PY - 2015/7/14

Y1 - 2015/7/14

N2 - Abstract The rhodium(III)-catalyzed ortho-C-H functionalization of 2-arylbenzo[d]thiazoles with α-diazo esters is described. This transformation provides the facile and efficient construction of C2-alkylated 2-arylbenzo[d]thiazoles in the absence of external oxidants, and releases benign N2 gas as the only byproduct.

AB - Abstract The rhodium(III)-catalyzed ortho-C-H functionalization of 2-arylbenzo[d]thiazoles with α-diazo esters is described. This transformation provides the facile and efficient construction of C2-alkylated 2-arylbenzo[d]thiazoles in the absence of external oxidants, and releases benign N2 gas as the only byproduct.

KW - 2-Arylbenzothiazole

KW - Alkylation

KW - C-H activation

KW - Diazo ester

KW - Rhodium

UR - https://www.scopus.com/pages/publications/84938201086

U2 - 10.1016/j.tetlet.2015.06.036

DO - 10.1016/j.tetlet.2015.06.036

M3 - Article

AN - SCOPUS:84938201086

SN - 0040-4039

VL - 56

SP - 4678

EP - 4682

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 32

M1 - 46428

ER -

Rh(III)-catalyzed C-H alkylation of 2-arylbenzothiazoles with α-diazo esters

Abstract

Keywords

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