Renal tissue reconstitution by the implantation of renal segments on biodegradable polymer scaffolds

Sang Soo Kim; Heung Jae Park; Joungho Han; Cha Yong Choi; Byung Soo Kim

doi:10.1023/A:1025490718221

Renal tissue reconstitution by the implantation of renal segments on biodegradable polymer scaffolds

Sang Soo Kim
, Heung Jae Park
, Joungho Han
, Cha Yong Choi
, Byung Soo Kim

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Renal units were created in vivo by transplanting isolated renal segments on three-dimensional, biodegradable polymer scaffolds. Renal segments, freshly isolated from rat kidneys, were seeded on polymer scaffolds and subcutaneously implanted in athymic mice for two and four weeks. Three-dimensional renal reconstructs were formed with glomeruli and tubules, showing a possibility of reconstituting renal structures by transplanting renal segments.

Original language	English
Pages (from-to)	1505-1508
Number of pages	4
Journal	Biotechnology Letters
Volume	25
Issue number	18
DOIs	https://doi.org/10.1023/A:1025490718221
State	Published - Sep 2003
Externally published	Yes

Keywords

Biodegradable polymer scaffold
Renal reconstitution
Tissue engineering

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10.1023/A:1025490718221

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abstract = "Renal units were created in vivo by transplanting isolated renal segments on three-dimensional, biodegradable polymer scaffolds. Renal segments, freshly isolated from rat kidneys, were seeded on polymer scaffolds and subcutaneously implanted in athymic mice for two and four weeks. Three-dimensional renal reconstructs were formed with glomeruli and tubules, showing a possibility of reconstituting renal structures by transplanting renal segments.",

keywords = "Biodegradable polymer scaffold, Renal reconstitution, Tissue engineering",

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AU - Kim, Sang Soo

AU - Park, Heung Jae

AU - Han, Joungho

AU - Choi, Cha Yong

AU - Kim, Byung Soo

PY - 2003/9

Y1 - 2003/9

N2 - Renal units were created in vivo by transplanting isolated renal segments on three-dimensional, biodegradable polymer scaffolds. Renal segments, freshly isolated from rat kidneys, were seeded on polymer scaffolds and subcutaneously implanted in athymic mice for two and four weeks. Three-dimensional renal reconstructs were formed with glomeruli and tubules, showing a possibility of reconstituting renal structures by transplanting renal segments.

AB - Renal units were created in vivo by transplanting isolated renal segments on three-dimensional, biodegradable polymer scaffolds. Renal segments, freshly isolated from rat kidneys, were seeded on polymer scaffolds and subcutaneously implanted in athymic mice for two and four weeks. Three-dimensional renal reconstructs were formed with glomeruli and tubules, showing a possibility of reconstituting renal structures by transplanting renal segments.

KW - Biodegradable polymer scaffold

KW - Renal reconstitution

KW - Tissue engineering

UR - https://www.scopus.com/pages/publications/0141453607

U2 - 10.1023/A:1025490718221

DO - 10.1023/A:1025490718221

M3 - Article

C2 - 14571973

AN - SCOPUS:0141453607

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VL - 25

SP - 1505

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JO - Biotechnology Letters

JF - Biotechnology Letters

IS - 18

ER -

Renal tissue reconstitution by the implantation of renal segments on biodegradable polymer scaffolds

Abstract

Keywords

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