Raised lateral patch clamp array in open-access fluidic system

Adrian Y. Lau; Paul J. Hung; Luke P. Lee

Raised lateral patch clamp array in open-access fluidic system

Adrian Y. Lau
, Paul J. Hung
, Luke P. Lee

University of California at Berkeley

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

A novel lateral patch-clamp array with cell trapping locations raised above the substrate was developed. The fabrication method creates an open-access fluidic system by involving both microfabrication and macro-machining processes. This paper demonstrates the capability of using such an open-access fluidic system for high throughput patch clamp measurements. Seal resistances over 350MΩ were measured consistently. Patch clamp recording were obtained with from Kv2.1 potassium transfected CHO cells.

Original language	English
Title of host publication	Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
Subtitle of host publication	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Transducer Research Foundation
Pages	442-444
Number of pages	3
ISBN (Print)	0974361119, 9780974361116
State	Published - 2005
Externally published	Yes
Event	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States Duration: 9 Oct 2005 → 13 Oct 2005

Publication series

Name	Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Volume	1

Conference

Conference	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
Country/Territory	United States
City	Boston, MA
Period	9/10/05 → 13/10/05

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 9 Industry, Innovation, and Infrastructure

Cite this

Lau, A. Y., Hung, P. J., & Lee, L. P. (2005). Raised lateral patch clamp array in open-access fluidic system. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 442-444). (Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences; Vol. 1). Transducer Research Foundation.

Lau, Adrian Y. ; Hung, Paul J. ; Lee, Luke P. / Raised lateral patch clamp array in open-access fluidic system. Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research Foundation, 2005. pp. 442-444 (Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

@inproceedings{83955452ce8949fba9fabab23b42460d,

title = "Raised lateral patch clamp array in open-access fluidic system",

abstract = "A novel lateral patch-clamp array with cell trapping locations raised above the substrate was developed. The fabrication method creates an open-access fluidic system by involving both microfabrication and macro-machining processes. This paper demonstrates the capability of using such an open-access fluidic system for high throughput patch clamp measurements. Seal resistances over 350MΩ were measured consistently. Patch clamp recording were obtained with from Kv2.1 potassium transfected CHO cells.",

author = "Lau, \{Adrian Y.\} and Hung, \{Paul J.\} and Lee, \{Luke P.\}",

year = "2005",

language = "English",

isbn = "0974361119",

series = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Transducer Research Foundation",

pages = "442--444",

booktitle = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference",

note = "9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 ; Conference date: 09-10-2005 Through 13-10-2005",

}

Lau, AY, Hung, PJ & Lee, LP 2005, Raised lateral patch clamp array in open-access fluidic system. in Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, vol. 1, Transducer Research Foundation, pp. 442-444, 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005, Boston, MA, United States, 9/10/05.

Raised lateral patch clamp array in open-access fluidic system. / Lau, Adrian Y.; Hung, Paul J.; Lee, Luke P.
Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research Foundation, 2005. p. 442-444 (Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Raised lateral patch clamp array in open-access fluidic system

AU - Lau, Adrian Y.

AU - Hung, Paul J.

AU - Lee, Luke P.

PY - 2005

Y1 - 2005

N2 - A novel lateral patch-clamp array with cell trapping locations raised above the substrate was developed. The fabrication method creates an open-access fluidic system by involving both microfabrication and macro-machining processes. This paper demonstrates the capability of using such an open-access fluidic system for high throughput patch clamp measurements. Seal resistances over 350MΩ were measured consistently. Patch clamp recording were obtained with from Kv2.1 potassium transfected CHO cells.

AB - A novel lateral patch-clamp array with cell trapping locations raised above the substrate was developed. The fabrication method creates an open-access fluidic system by involving both microfabrication and macro-machining processes. This paper demonstrates the capability of using such an open-access fluidic system for high throughput patch clamp measurements. Seal resistances over 350MΩ were measured consistently. Patch clamp recording were obtained with from Kv2.1 potassium transfected CHO cells.

UR - https://www.scopus.com/pages/publications/52249119100

M3 - Conference contribution

AN - SCOPUS:52249119100

SN - 0974361119

SN - 9780974361116

T3 - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences

SP - 442

EP - 444

BT - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference

PB - Transducer Research Foundation

T2 - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005

Y2 - 9 October 2005 through 13 October 2005

ER -

Lau AY, Hung PJ, Lee LP. Raised lateral patch clamp array in open-access fluidic system. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research Foundation. 2005. p. 442-444. (Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Raised lateral patch clamp array in open-access fluidic system

Abstract

Publication series

Conference

UN SDGs

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