Abstract
Biodegradable hydrogels based on synthetic PHEA and IPN type composite hydrogel with chitosan, a natural carbohydrate polymer, were prepared by crosslinking using glutaraldehyde in aqueous mixture. Relatively strong hydrogels were formed in a shaped mold. Preparation of crosslinked gels and their swelling behavior depending on the composition, medium, and pH of solution are investigated. The porous morphology of scaffolds, obtained by freeze-drying method, was observed by scanning electron microscopy. Also preliminary results/on hydrolytic degradation and cytotoxicity test of the hydrogel are included.
| Original language | English |
|---|---|
| Pages (from-to) | 943-948 |
| Number of pages | 6 |
| Journal | Polymer Journal |
| Volume | 36 |
| Issue number | 12 |
| DOIs | |
| State | Published - 2004 |
Keywords
- Biodegradation
- Chitosan
- Hydrogel
- pH-Sensitive
- Polyhydroxyethyl aspartamide
- Scaffold
- Swelling Behavior
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