Physician- and self-assessed myasthenia gravis activities of daily living score

Hye Lim Lee, Ju Hong Min, Jin Myoung Seok, Eun Bin Cho, Hye Jin Cho, Yong Dae Kim, Byoung Joon Kim

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Introduction: The Myasthenia Gravis—Activities of Daily Living (MG-ADL) profile scale is a simple-to-use instrument. We aimed to validate this scale in the Korean language and compare physician- and self-assessed MG-ADL scores (pMG-ADL-K and sMG-ADL-K). Methods: pMG-ADL-K and sMG-ADL-K and MG Composite (MGC) scores were obtained from patients. The correlation between pMG-ADL-K and MGC and the relationship between the pMG-ADL-K and sMG-ADL-K were assessed using the Cronbach α and the Spearman coefficient. By intraclass correlation coefficient (ICC), the reliability of each sub-item of pMG-ADL-K and sMG-ADL-K was evaluated. Results: We included data from 40 patients. The pMG-ADL-K score showed a strong correlation with the MGC score (rho = 0.80, P < 0.01). The Cronbach α was 0.98 between pMG-ADL-K and sMG-ADL-K, and sub-items showed good consistency (ICC 0.684–0.985, P < 0.001). Discussion: The MG-ADL-K is a valid tool and the sMG-ADL-K shows excellent correlation with pMG-ADL-K. Both the pMG-ADL-K and sMG-ADL-K can be used to measure MG severity. Muscle Nerve 57: 419–422, 2018.

Original languageEnglish
Pages (from-to)419-422
Number of pages4
JournalMuscle and Nerve
Volume57
Issue number3
DOIs
StatePublished - Mar 2018

Keywords

  • MG clinical trial
  • MG Composite scale
  • MG-ADL
  • myasthenia gravis
  • myasthenia gravis scales
  • Myasthenia Gravis—Activities of Daily Living profile

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