Pd(ii)-catalyzed direct C-H acylation of N-Boc hydrazones with aldehydes: One-pot synthesis of 1,2-diacylbenzenes

Satyasheel Sharma; Aejin Kim; Jihye Park; Mirim Kim; Jong Hwan Kwak; Young Hoon Jung; Jung Su Park; In Su Kim

doi:10.1039/c3ob41644e

Pd(ii)-catalyzed direct C-H acylation of N-Boc hydrazones with aldehydes: One-pot synthesis of 1,2-diacylbenzenes

Satyasheel Sharma, Aejin Kim, Jihye Park, Mirim Kim, Jong Hwan Kwak, Young Hoon Jung, Jung Su Park, In Su Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

A palladium(ii)-catalyzed direct acylation of acetophenone N-Boc hydrazones with aldehydes via C-H bond activation is described. This protocol provides direct access to a range of 1,2-diacylbenzenes, which are useful precursors to construct biologically interesting and pharmaceutically important compounds.

Original language	English
Pages (from-to)	7869-7876
Number of pages	8
Journal	Organic and Biomolecular Chemistry
Volume	11
Issue number	45
DOIs	https://doi.org/10.1039/c3ob41644e
State	Published - 7 Dec 2013

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abstract = "A palladium(ii)-catalyzed direct acylation of acetophenone N-Boc hydrazones with aldehydes via C-H bond activation is described. This protocol provides direct access to a range of 1,2-diacylbenzenes, which are useful precursors to construct biologically interesting and pharmaceutically important compounds.",

author = "Satyasheel Sharma and Aejin Kim and Jihye Park and Mirim Kim and Kwak, \{Jong Hwan\} and Jung, \{Young Hoon\} and Park, \{Jung Su\} and Kim, \{In Su\}",

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T1 - Pd(ii)-catalyzed direct C-H acylation of N-Boc hydrazones with aldehydes

T2 - One-pot synthesis of 1,2-diacylbenzenes

AU - Sharma, Satyasheel

AU - Kim, Aejin

AU - Park, Jihye

AU - Kim, Mirim

AU - Kwak, Jong Hwan

AU - Jung, Young Hoon

AU - Park, Jung Su

AU - Kim, In Su

PY - 2013/12/7

Y1 - 2013/12/7

N2 - A palladium(ii)-catalyzed direct acylation of acetophenone N-Boc hydrazones with aldehydes via C-H bond activation is described. This protocol provides direct access to a range of 1,2-diacylbenzenes, which are useful precursors to construct biologically interesting and pharmaceutically important compounds.

AB - A palladium(ii)-catalyzed direct acylation of acetophenone N-Boc hydrazones with aldehydes via C-H bond activation is described. This protocol provides direct access to a range of 1,2-diacylbenzenes, which are useful precursors to construct biologically interesting and pharmaceutically important compounds.

UR - https://www.scopus.com/pages/publications/84886837985

U2 - 10.1039/c3ob41644e

DO - 10.1039/c3ob41644e

M3 - Article

C2 - 24129548

AN - SCOPUS:84886837985

SN - 1477-0520

VL - 11

SP - 7869

EP - 7876

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 45

ER -

Pd(ii)-catalyzed direct C-H acylation of N-Boc hydrazones with aldehydes: One-pot synthesis of 1,2-diacylbenzenes

Abstract

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