Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation

Jihye Park; Minyoung Kim; Satyasheel Sharma; Eonjeong Park; Aejin Kim; Sang Hwi Lee; Jong Hwan Kwak; Young Hoon Jung; In Su Kim

doi:10.1039/c3cc38764j

Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation

Jihye Park, Minyoung Kim, Satyasheel Sharma, Eonjeong Park, Aejin Kim, Sang Hwi Lee, Jong Hwan Kwak, Young Hoon Jung, In Su Kim

Department of Pharmacy

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

120 Scopus citations

Abstract

A palladium-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation is described. This protocol provides efficient access to a range of ortho-acyl phenylacetamides, which can be easily converted to 3-isochromanone derivatives.

Original language	English
Pages (from-to)	1654-1656
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	16
DOIs	https://doi.org/10.1039/c3cc38764j
State	Published - 29 Jan 2013

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title = "Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation",

abstract = "A palladium-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation is described. This protocol provides efficient access to a range of ortho-acyl phenylacetamides, which can be easily converted to 3-isochromanone derivatives.",

author = "Jihye Park and Minyoung Kim and Satyasheel Sharma and Eonjeong Park and Aejin Kim and Lee, \{Sang Hwi\} and Kwak, \{Jong Hwan\} and Jung, \{Young Hoon\} and Kim, \{In Su\}",

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T1 - Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation

AU - Park, Jihye

AU - Kim, Minyoung

AU - Sharma, Satyasheel

AU - Park, Eonjeong

AU - Kim, Aejin

AU - Lee, Sang Hwi

AU - Kwak, Jong Hwan

AU - Jung, Young Hoon

AU - Kim, In Su

PY - 2013/1/29

Y1 - 2013/1/29

N2 - A palladium-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation is described. This protocol provides efficient access to a range of ortho-acyl phenylacetamides, which can be easily converted to 3-isochromanone derivatives.

AB - A palladium-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation is described. This protocol provides efficient access to a range of ortho-acyl phenylacetamides, which can be easily converted to 3-isochromanone derivatives.

UR - https://www.scopus.com/pages/publications/84873279427

U2 - 10.1039/c3cc38764j

DO - 10.1039/c3cc38764j

M3 - Article

C2 - 23334232

AN - SCOPUS:84873279427

SN - 1359-7345

VL - 49

SP - 1654

EP - 1656

JO - Chemical Communications

JF - Chemical Communications

IS - 16

ER -

Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation

Abstract

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