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Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation

  • Jihye Park
  • , Minyoung Kim
  • , Satyasheel Sharma
  • , Eonjeong Park
  • , Aejin Kim
  • , Sang Hwi Lee
  • , Jong Hwan Kwak
  • , Young Hoon Jung
  • , In Su Kim
  • Sungkyunkwan University

Research output: Contribution to journalArticlepeer-review

Abstract

A palladium-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C–H bond activation is described. This protocol provides efficient access to a range of ortho-acyl phenylacetamides, which can be easily converted to 3-isochromanone derivatives.

Original languageEnglish
Pages (from-to)1654-1656
Number of pages3
JournalChemical Communications
Volume49
Issue number16
DOIs
StatePublished - 29 Jan 2013

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