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PBPK modeling to predict the pharmacokinetics of venlafaxine and its active metabolite in different CYP2D6 genotypes and drug–drug interactions with clarithromycin and paroxetine

  • Chang Keun Cho
  • , Pureum Kang
  • , Choon Gon Jang
  • , Seok Yong Lee
  • , Yun Jeong Lee
  • , Jung Woo Bae
  • , Chang Ik Choi
  • Sungkyunkwan University
  • Dankook University
  • Keimyung University
  • Dongguk University

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Pharmacology, Toxicology and Pharmaceutical Science