Patterned Poly(dopamine) films for enhanced cell adhesion

Xi Chen; Christina Cortez-Jugo; Gwan H. Choi; Mattias Björnmalm; Yunlu Dai; Pil J. Yoo; Frank Caruso

doi:10.1021/acs.bioconjchem.6b00544

Patterned Poly(dopamine) films for enhanced cell adhesion

Xi Chen
, Christina Cortez-Jugo
, Gwan H. Choi
, Mattias Björnmalm
, Yunlu Dai
, Pil J. Yoo
, Frank Caruso

Department of Chemical Engineering

University of Melbourne
Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Engineered materials that promote cell adhesion and cell growth are important in tissue engineering and regenerative medicine. In this work, we produced poly(dopamine) (PDA) films with engineered patterns for improved cell adhesion. The patterned films were synthesized via the polymerization of dopamine at the air-water interface of a floating bed of spherical particles. Subsequent dissolution of the particles yielded free-standing PDA films with tunable geometrical patterns. Our results show that these patterned PDA films significantly enhance the adhesion of both cancer cells and stem cells, thus showing promise as substrates for cell attachment for various biomedical applications.

Original language	English
Pages (from-to)	75-80
Number of pages	6
Journal	Bioconjugate Chemistry
Volume	28
Issue number	1
DOIs	https://doi.org/10.1021/acs.bioconjchem.6b00544
State	Published - 18 Jan 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1021/acs.bioconjchem.6b00544

Cite this

@article{d25a8d61a00942898196ccf7ccc55f00,

title = "Patterned Poly(dopamine) films for enhanced cell adhesion",

abstract = "Engineered materials that promote cell adhesion and cell growth are important in tissue engineering and regenerative medicine. In this work, we produced poly(dopamine) (PDA) films with engineered patterns for improved cell adhesion. The patterned films were synthesized via the polymerization of dopamine at the air-water interface of a floating bed of spherical particles. Subsequent dissolution of the particles yielded free-standing PDA films with tunable geometrical patterns. Our results show that these patterned PDA films significantly enhance the adhesion of both cancer cells and stem cells, thus showing promise as substrates for cell attachment for various biomedical applications.",

author = "Xi Chen and Christina Cortez-Jugo and Choi, \{Gwan H.\} and Mattias Bj{\"o}rnmalm and Yunlu Dai and Yoo, \{Pil J.\} and Frank Caruso",

note = "Publisher Copyright: {\textcopyright} 2016 American Chemical Society.",

year = "2017",

month = jan,

day = "18",

doi = "10.1021/acs.bioconjchem.6b00544",

language = "English",

volume = "28",

pages = "75--80",

journal = "Bioconjugate Chemistry",

issn = "1043-1802",

publisher = "American Chemical Society",

number = "1",

}

TY - JOUR

T1 - Patterned Poly(dopamine) films for enhanced cell adhesion

AU - Chen, Xi

AU - Cortez-Jugo, Christina

AU - Choi, Gwan H.

AU - Björnmalm, Mattias

AU - Dai, Yunlu

AU - Yoo, Pil J.

AU - Caruso, Frank

PY - 2017/1/18

Y1 - 2017/1/18

N2 - Engineered materials that promote cell adhesion and cell growth are important in tissue engineering and regenerative medicine. In this work, we produced poly(dopamine) (PDA) films with engineered patterns for improved cell adhesion. The patterned films were synthesized via the polymerization of dopamine at the air-water interface of a floating bed of spherical particles. Subsequent dissolution of the particles yielded free-standing PDA films with tunable geometrical patterns. Our results show that these patterned PDA films significantly enhance the adhesion of both cancer cells and stem cells, thus showing promise as substrates for cell attachment for various biomedical applications.

AB - Engineered materials that promote cell adhesion and cell growth are important in tissue engineering and regenerative medicine. In this work, we produced poly(dopamine) (PDA) films with engineered patterns for improved cell adhesion. The patterned films were synthesized via the polymerization of dopamine at the air-water interface of a floating bed of spherical particles. Subsequent dissolution of the particles yielded free-standing PDA films with tunable geometrical patterns. Our results show that these patterned PDA films significantly enhance the adhesion of both cancer cells and stem cells, thus showing promise as substrates for cell attachment for various biomedical applications.

UR - https://www.scopus.com/pages/publications/85021860331

U2 - 10.1021/acs.bioconjchem.6b00544

DO - 10.1021/acs.bioconjchem.6b00544

M3 - Article

C2 - 28095687

AN - SCOPUS:85021860331

SN - 1043-1802

VL - 28

SP - 75

EP - 80

JO - Bioconjugate Chemistry

JF - Bioconjugate Chemistry

IS - 1

ER -

Patterned Poly(dopamine) films for enhanced cell adhesion

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this