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Oral iptacopan monotherapy in paroxysmal nocturnal haemoglobinuria: final 48-week results from the open-label, randomised, phase 3 APPLY-PNH trial in anti-C5-treated patients and the open-label, single-arm, phase 3 APPOINT-PNH trial in patients previously untreated with complement inhibitors

  • Antonio M. Risitano
  • , Austin G. Kulasekararaj
  • , Phillip Scheinberg
  • , Alexander Röth
  • , Bing Han
  • , Jaroslaw P. Maciejewski
  • , Yasutaka Ueda
  • , Carlos M. de Castro
  • , Eros Di Bona
  • , Rong Fu
  • , Li Zhang
  • , Morag Griffin
  • , Saskia M.C. Langemeijer
  • , Jens Panse
  • , Hubert Schrezenmeier
  • , Wilma Barcellini
  • , Vitor A.Q. Mauad
  • , Philippe Schafhausen
  • , Suzanne Tavitian
  • , Eloise Beggiato
    • Lee Ping Chew, Anna Gaya, Wei Han Huang, Jun Ho Jang, Toshio Kitawaki, Abdullah Kutlar, Rosario Notaro, Vinod Pullarkat, Jörg Schubert, Louis Terriou, Michihiro Uchiyama, Lily Wong Lee Lee, Eng Soo Yap, Camilla Frieri, Luana Marano, Flore Sicre de Fontbrune, Shreyans Gandhi, Roochi Trikha, Ferras Alashkar, Chen Yang, Hui Liu, Richard J. Kelly, Britta Höchsmann, Tomasz Lawniczek, Navin Mahajan, Susan Solar-Yohay, Cécile Kerloëguen, Philippe Ferber, Rakesh Kumar, Zhixin Wang, Christine Thorburn, Samopriyo Maitra, Shujie Li, Aurelie Verles, Marion Dahlke, Régis Peffault de Latour
  • AORN Moscati
  • University of Naples Federico II
  • King's College Hospital NHS Foundation Trust
  • National Institute for Health and Care Research
  • King's College London
  • Hospital A Beneficência Portuguesa
  • University of Duisburg-Essen
  • Chinese Academy of Medical Sciences
  • Cleveland Clinic Foundation
  • The University of Osaka
  • Duke University
  • Bassano del Grappa (VI)
  • Tianjin Medical University
  • Leeds Teaching Hospitals NHS Trust
  • Radboud University Nijmegen
  • RWTH Aachen University
  • University Hospital of Cologne
  • Ulm University
  • German Red Cross Blood Transfusion Service Baden-Württemberg-Hessen and University Hospital Ulm
  • IRCCS Fondazione Ca'Granda – Ospedale Maggiore Policlinico - Milano
  • ABC Medical School
  • University of Hamburg
  • CHU de Toulouse
  • University of Turin
  • Kementerian Kesihatan Malaysia
  • Hospital Clinic Barcelona
  • Buddhist Tzu-Chi General Hospital Taiwan
  • Tzu Chi University
  • Kyoto University
  • Augusta University
  • Azienda Ospedaliera Careggi
  • Institute for the Study and Prevention of Cancer
  • City of Hope National Med Center
  • Elblandklinikum Riesa
  • Université de Lille
  • Japanese Red Cross Suwa Hospital
  • Queen Elizabeth Hospital
  • National University Hospital
  • Université Paris Cité
  • Novartis

Research output: Contribution to journal › Article › peer-review

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