TY - JOUR
T1 - Optimisation of a hybrid photoneutron source in a linear accelerator using GEANT4 and MCNPX Monte Carlo codes
AU - Ghergherehchi, Mitra
AU - Ko, Junho
AU - ArabyarMohammadi, Narjes
AU - Afarideh, Hossein
AU - Kim, Yoon Sang
N1 - Publisher Copyright:
© 2018, Indian Academy of Sciences.
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Radiotherapy is important for treating oral cancer in advanced stages. Boron neutron capture therapy represents a unique modality in which neutron beams penetrate into the tissue within an epithermal range. Different methods are available for neutron production, and in this study, we used an electron accelerator. A photoneutron source based on three different energy values (10, 25, and 50 MeV) of a linear accelerator electron beam was designed using GEANT4 (GEometry ANd Tracking) and MCNPX (Monte Carlo N-Particle eXtended) simulation codes. The results indicate that a hybrid photoneutron source introduced tungsten and uranium with BeO. The statistical uncertainties in all simulations were less than 0.3 and 0.07% for MCNPX and the standard electromagnetic physics packages of GEANT4, respectively. Various cross-sectional and stopping-power data and different physics simulations produced different distributions.
AB - Radiotherapy is important for treating oral cancer in advanced stages. Boron neutron capture therapy represents a unique modality in which neutron beams penetrate into the tissue within an epithermal range. Different methods are available for neutron production, and in this study, we used an electron accelerator. A photoneutron source based on three different energy values (10, 25, and 50 MeV) of a linear accelerator electron beam was designed using GEANT4 (GEometry ANd Tracking) and MCNPX (Monte Carlo N-Particle eXtended) simulation codes. The results indicate that a hybrid photoneutron source introduced tungsten and uranium with BeO. The statistical uncertainties in all simulations were less than 0.3 and 0.07% for MCNPX and the standard electromagnetic physics packages of GEANT4, respectively. Various cross-sectional and stopping-power data and different physics simulations produced different distributions.
KW - 00.02
KW - 20.24
KW - boron neutron capture therapy
KW - Hybrid photoneutron
KW - statistical uncertainty
UR - https://www.scopus.com/pages/publications/85050618114
U2 - 10.1007/s12043-018-1606-1
DO - 10.1007/s12043-018-1606-1
M3 - Article
AN - SCOPUS:85050618114
SN - 0304-4289
VL - 91
JO - Pramana - Journal of Physics
JF - Pramana - Journal of Physics
IS - 3
M1 - 35
ER -