Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review

Jin Young Lee; Gil Ho Lee; Seung Hyun Yi; Woo Seog Sim; Bae Wook Kim; Hue Jung Park

doi:10.3390/biomedicines11082315

Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review

Jin Young Lee
, Gil Ho Lee
, Seung Hyun Yi
, Woo Seog Sim
, Bae Wook Kim
, Hue Jung Park

Department of Anesthesiology and Pain Medicine

The Catholic University of Korea

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Trigeminal neuralgia (TN) is a unilateral disorder characterized by electric shock-like pain, abrupt onset and termination, and limited to one or more branches of the trigeminal nerve. Various therapeutic modalities for TN have been introduced. We searched for literature indexed in PubMed, Medline, and the National Library of Medicine and reviewed all relevant articles on non-surgical treatments for TN. Published studies were reviewed with no restrictions on date; reviews, clinical trials, animal studies, retrospective studies, and cases were included. Carbamazepine and oxcarbazepine are the recommended first-line pharmacotherapies. Interventional treatments should be considered when pharmacotherapy is insufficient or withdrawn because of adverse effects.

Original language	English
Article number	2315
Journal	Biomedicines
Volume	11
Issue number	8
DOIs	https://doi.org/10.3390/biomedicines11082315
State	Published - Aug 2023

Keywords

intervention
pain
pharmacotherapy
treatment
trigeminal neuralgia

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10.3390/biomedicines11082315

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title = "Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review",

abstract = "Trigeminal neuralgia (TN) is a unilateral disorder characterized by electric shock-like pain, abrupt onset and termination, and limited to one or more branches of the trigeminal nerve. Various therapeutic modalities for TN have been introduced. We searched for literature indexed in PubMed, Medline, and the National Library of Medicine and reviewed all relevant articles on non-surgical treatments for TN. Published studies were reviewed with no restrictions on date; reviews, clinical trials, animal studies, retrospective studies, and cases were included. Carbamazepine and oxcarbazepine are the recommended first-line pharmacotherapies. Interventional treatments should be considered when pharmacotherapy is insufficient or withdrawn because of adverse effects.",

keywords = "intervention, pain, pharmacotherapy, treatment, trigeminal neuralgia",

author = "Lee, \{Jin Young\} and Lee, \{Gil Ho\} and Yi, \{Seung Hyun\} and Sim, \{Woo Seog\} and Kim, \{Bae Wook\} and Park, \{Hue Jung\}",

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doi = "10.3390/biomedicines11082315",

language = "English",

volume = "11",

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T2 - A Narrative Review

AU - Lee, Jin Young

AU - Lee, Gil Ho

AU - Yi, Seung Hyun

AU - Sim, Woo Seog

AU - Kim, Bae Wook

AU - Park, Hue Jung

PY - 2023/8

Y1 - 2023/8

N2 - Trigeminal neuralgia (TN) is a unilateral disorder characterized by electric shock-like pain, abrupt onset and termination, and limited to one or more branches of the trigeminal nerve. Various therapeutic modalities for TN have been introduced. We searched for literature indexed in PubMed, Medline, and the National Library of Medicine and reviewed all relevant articles on non-surgical treatments for TN. Published studies were reviewed with no restrictions on date; reviews, clinical trials, animal studies, retrospective studies, and cases were included. Carbamazepine and oxcarbazepine are the recommended first-line pharmacotherapies. Interventional treatments should be considered when pharmacotherapy is insufficient or withdrawn because of adverse effects.

AB - Trigeminal neuralgia (TN) is a unilateral disorder characterized by electric shock-like pain, abrupt onset and termination, and limited to one or more branches of the trigeminal nerve. Various therapeutic modalities for TN have been introduced. We searched for literature indexed in PubMed, Medline, and the National Library of Medicine and reviewed all relevant articles on non-surgical treatments for TN. Published studies were reviewed with no restrictions on date; reviews, clinical trials, animal studies, retrospective studies, and cases were included. Carbamazepine and oxcarbazepine are the recommended first-line pharmacotherapies. Interventional treatments should be considered when pharmacotherapy is insufficient or withdrawn because of adverse effects.

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KW - pain

KW - pharmacotherapy

KW - treatment

KW - trigeminal neuralgia

UR - https://www.scopus.com/pages/publications/85168916379

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DO - 10.3390/biomedicines11082315

M3 - Review article

AN - SCOPUS:85168916379

SN - 2227-9059

VL - 11

JO - Biomedicines

JF - Biomedicines

IS - 8

M1 - 2315

ER -

Non-Surgical Treatments of Trigeminal Neuralgia from the Perspective of a Pain Physician: A Narrative Review

Abstract

Keywords

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