Abstract
We describe two cases of multifocal lymphadenopathy due to concurrent cytomegalovirus and Epstein-Barr virus infections after chemotherapy for diffuse large B-cell lymphoma. The patients presented with suspected local recurrence on computed tomography and positron emission tomography-computed tomography at 19 and 8 months after completion of chemotherapy, but neither had any signs of systemic involvement. The enlarged lymph nodes resolved spontaneously without treatment after 2 and 12 weeks, respectively. A compromised cellular immune system after chemotherapy may have allowed the viral infection. This report demonstrates that multifocal lymphadenopathy due to viral infection after chemotherapy in aggressive B-cell lymphoma can mimic tumor recurrence, and that spontaneous resolution without antiviral agents can be achieved.
| Original language | English |
|---|---|
| Pages (from-to) | 8745-8749 |
| Number of pages | 5 |
| Journal | International Journal of Clinical and Experimental Pathology |
| Volume | 9 |
| Issue number | 8 |
| State | Published - 2016 |
| Externally published | Yes |
Keywords
- Cytomegalovirus
- Epstein-Barr virus
- Lymphadenopathy
- Lymphoma
- Recurrence
