Mirabegron Add-on Therapy to Tamsulosin for the Treatment of Overactive Bladder in Men with Lower Urinary Tract Symptoms: A Randomized, Placebo-controlled Study (MATCH)

Hidehiro Kakizaki; Kyu Sung Lee; Osamu Yamamoto; Jar Jar Jong; Daisuke Katou; Budiwan Sumarsono; Satoshi Uno; Osamu Yamaguchi

doi:10.1016/j.euf.2019.10.019

Mirabegron Add-on Therapy to Tamsulosin for the Treatment of Overactive Bladder in Men with Lower Urinary Tract Symptoms: A Randomized, Placebo-controlled Study (MATCH)

Hidehiro Kakizaki
, Kyu Sung Lee
, Osamu Yamamoto
, Jar Jar Jong
, Daisuke Katou
, Budiwan Sumarsono
, Satoshi Uno
, Osamu Yamaguchi

Department of Urology

Asahikawa Medical University
Astellas Pharma Inc.
Astellas Pharma Singapore Pte. Ltd
Nihon University

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Abstract

We evaluated the efficacy and safety of mirabegron versus placebo in men with overactive bladder symptoms treated with tamsulosin. Adding mirabegron to tamsulosin improved symptoms of overactive bladder compared with placebo and was well tolerated.

Original language	English
Pages (from-to)	729-737
Number of pages	9
Journal	European Urology Focus
Volume	6
Issue number	4
DOIs	https://doi.org/10.1016/j.euf.2019.10.019
State	Published - 15 Jul 2020

Keywords

Combination therapy
Efficacy
Mirabegron
Overactive bladder
Tamsulosin
Tolerability
α-Blocker

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10.1016/j.euf.2019.10.019

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title = "Mirabegron Add-on Therapy to Tamsulosin for the Treatment of Overactive Bladder in Men with Lower Urinary Tract Symptoms: A Randomized, Placebo-controlled Study (MATCH)",

abstract = "We evaluated the efficacy and safety of mirabegron versus placebo in men with overactive bladder symptoms treated with tamsulosin. Adding mirabegron to tamsulosin improved symptoms of overactive bladder compared with placebo and was well tolerated.",

keywords = "Combination therapy, Efficacy, Mirabegron, Overactive bladder, Tamsulosin, Tolerability, α-Blocker",

author = "Hidehiro Kakizaki and Lee, \{Kyu Sung\} and Osamu Yamamoto and Jong, \{Jar Jar\} and Daisuke Katou and Budiwan Sumarsono and Satoshi Uno and Osamu Yamaguchi",

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T1 - Mirabegron Add-on Therapy to Tamsulosin for the Treatment of Overactive Bladder in Men with Lower Urinary Tract Symptoms

T2 - A Randomized, Placebo-controlled Study (MATCH)

AU - Kakizaki, Hidehiro

AU - Lee, Kyu Sung

AU - Yamamoto, Osamu

AU - Jong, Jar Jar

AU - Katou, Daisuke

AU - Sumarsono, Budiwan

AU - Uno, Satoshi

AU - Yamaguchi, Osamu

PY - 2020/7/15

Y1 - 2020/7/15

N2 - We evaluated the efficacy and safety of mirabegron versus placebo in men with overactive bladder symptoms treated with tamsulosin. Adding mirabegron to tamsulosin improved symptoms of overactive bladder compared with placebo and was well tolerated.

AB - We evaluated the efficacy and safety of mirabegron versus placebo in men with overactive bladder symptoms treated with tamsulosin. Adding mirabegron to tamsulosin improved symptoms of overactive bladder compared with placebo and was well tolerated.

KW - Combination therapy

KW - Efficacy

KW - Mirabegron

KW - Overactive bladder

KW - Tamsulosin

KW - Tolerability

KW - α-Blocker

UR - https://www.scopus.com/pages/publications/85075537827

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DO - 10.1016/j.euf.2019.10.019

M3 - Article

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AN - SCOPUS:85075537827

SN - 2405-4569

VL - 6

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JF - European Urology Focus

IS - 4

ER -

Mirabegron Add-on Therapy to Tamsulosin for the Treatment of Overactive Bladder in Men with Lower Urinary Tract Symptoms: A Randomized, Placebo-controlled Study (MATCH)

Abstract

Keywords

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