Microchip capillary electrophoresis based separation and detection of cysteine and homocysteine

  • Rohit Chand
  • , Dawoon Han
  • , Kamrul Islam
  • , Ik Jun Yeon
  • , Sung Sik Ko
  • , Yong Sang Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Cysteine and homocysteine are the biological thiols which have an important function in various biochemical processes in our body. Alterations in their level lead to various abnormalities. Therefore, we fabricated a miniaturized platform for capillary electrophoresis that could separate and detect these amino thiols electrochemically. The device was fabricated using conventional photolithography technique on the glass substrate. The microchannel was molded in polydimethylsiloxane with gold electrodes deposited on glass for separation and detection. Based on the amperometric detection, we could detect cysteine in 93 sec while homocysteine was detected in 111 sec.

Original languageEnglish
Title of host publicationBiomaterial and Bioengineering
Pages482-486
Number of pages5
DOIs
StatePublished - 2013
Externally publishedYes
Event2012 International Conference on Biomaterial and Bioengineering, ICBB 2012 - , Hong Kong
Duration: 19 Dec 201220 Dec 2012

Publication series

NameAdvanced Materials Research
Volume647
ISSN (Print)1022-6680

Conference

Conference2012 International Conference on Biomaterial and Bioengineering, ICBB 2012
Country/TerritoryHong Kong
Period19/12/1220/12/12

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 9 - Industry, Innovation, and Infrastructure
    SDG 9 Industry, Innovation, and Infrastructure

Keywords

  • Capillary electrophoresis
  • Lab-on-a-chip
  • Microfabrication
  • Thiols
  • Voltammetry

Fingerprint

Dive into the research topics of 'Microchip capillary electrophoresis based separation and detection of cysteine and homocysteine'. Together they form a unique fingerprint.

Cite this