TY - JOUR
T1 - Left lobe living donor liver transplantation using the resection and partial liver segment 2–3 transplantation with delayed total hepatectomy (RAPID) procedure in cirrhotic patients
T2 - First case report in Korea
AU - Kim, Jongman
AU - Rhu, Jinsoo
AU - Lee, Eunjin
AU - Ryu, Youngju
AU - An, Sunghyo
AU - Jo, Sung Jun
AU - Oh, Namkee
AU - Han, Seungwook
AU - Park, Sunghae
AU - Choi, Gyu Seong
N1 - Publisher Copyright:
© The Korean Association of Hepato-Biliary-Pancreatic Surgery.
PY - 2024/8
Y1 - 2024/8
N2 - In liver transplantation, the primary concern is to ensure an adequate future liver remnant (FLR) volume for the donor, while selecting a graft of sufficient size for the recipient. The living donor–resection and partial liver segment 2−3 transplantation with delayed total hepatectomy (LD−RAPID) procedure offers a potential solution to expand the donor pool for living donor liver transplantation (LDLT). We report the first case involving a cirrhotic patient with autoimmune hepatitis and hepatocellular carcinoma, who underwent left lobe LDLT using the LD−RAPID procedure. The living liver donor (LLD) underwent a laparoscopic left hepatectomy, including middle hepatic vein. The resection on the recipient side was an extended left hepatectomy, including the middle hepatic vein orifice and caudate lobe. At postoperative day 7, a computed tomography scan showed hypertrophy of the left graft from 320 g to 465 mL (i.e., a 45.3% increase in graft volume body weight ratio from 0.60% to 0.77%). After a 7-day interval, the diseased right lobe was removed in the second stage surgery. The LD−RAPID procedure using left lobe graft allows for the use of a small liver graft or small FLR volume in LLD in LDLT, which expands the donor pool to minimize the risk to LLD by enabling the donation of a smaller liver portion.
AB - In liver transplantation, the primary concern is to ensure an adequate future liver remnant (FLR) volume for the donor, while selecting a graft of sufficient size for the recipient. The living donor–resection and partial liver segment 2−3 transplantation with delayed total hepatectomy (LD−RAPID) procedure offers a potential solution to expand the donor pool for living donor liver transplantation (LDLT). We report the first case involving a cirrhotic patient with autoimmune hepatitis and hepatocellular carcinoma, who underwent left lobe LDLT using the LD−RAPID procedure. The living liver donor (LLD) underwent a laparoscopic left hepatectomy, including middle hepatic vein. The resection on the recipient side was an extended left hepatectomy, including the middle hepatic vein orifice and caudate lobe. At postoperative day 7, a computed tomography scan showed hypertrophy of the left graft from 320 g to 465 mL (i.e., a 45.3% increase in graft volume body weight ratio from 0.60% to 0.77%). After a 7-day interval, the diseased right lobe was removed in the second stage surgery. The LD−RAPID procedure using left lobe graft allows for the use of a small liver graft or small FLR volume in LLD in LDLT, which expands the donor pool to minimize the risk to LLD by enabling the donation of a smaller liver portion.
KW - Directed tissue donation
KW - Living donor
KW - Tissue and organ procurement
KW - Transplantation
UR - https://www.scopus.com/pages/publications/85203584567
U2 - 10.14701/ahbps.24-005
DO - 10.14701/ahbps.24-005
M3 - Article
AN - SCOPUS:85203584567
SN - 2508-5778
VL - 28
SP - 388
EP - 392
JO - Annals of Hepato-Biliary-Pancreatic Surgery
JF - Annals of Hepato-Biliary-Pancreatic Surgery
IS - 3
ER -