ISAba15 inserted into outer membrane protein gene carO in Acinetobacter baumannii

Dae Hun Kim; Kwan Soo Ko

doi:10.4167/jbv.2015.45.1.51

ISAba15 inserted into outer membrane protein gene carO in Acinetobacter baumannii

Dae Hun Kim
, Kwan Soo Ko

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We identified ISAba15 inserted into the carO gene in an Acinetobacter baumannii isolate. The insert disrupted the lpxD gene, resulting in colistin resistance in A. baumannii. Persistence in carbapenem resistance in A. baumannii isolates with an intact carO gene indicates that loss of the encoded CarO may play a minor role in carbapenem resistance.

Original language	English
Pages (from-to)	51-53
Number of pages	3
Journal	Journal of Bacteriology and Virology
Volume	45
Issue number	1
DOIs	https://doi.org/10.4167/jbv.2015.45.1.51
State	Published - 2015
Externally published	Yes

Keywords

Antimicrobial resistance
Carbapenem
Insertion sequence (IS)

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10.4167/jbv.2015.45.1.51

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title = "ISAba15 inserted into outer membrane protein gene carO in Acinetobacter baumannii",

abstract = "We identified ISAba15 inserted into the carO gene in an Acinetobacter baumannii isolate. The insert disrupted the lpxD gene, resulting in colistin resistance in A. baumannii. Persistence in carbapenem resistance in A. baumannii isolates with an intact carO gene indicates that loss of the encoded CarO may play a minor role in carbapenem resistance.",

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year = "2015",

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AU - Kim, Dae Hun

AU - Ko, Kwan Soo

PY - 2015

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AB - We identified ISAba15 inserted into the carO gene in an Acinetobacter baumannii isolate. The insert disrupted the lpxD gene, resulting in colistin resistance in A. baumannii. Persistence in carbapenem resistance in A. baumannii isolates with an intact carO gene indicates that loss of the encoded CarO may play a minor role in carbapenem resistance.

KW - Antimicrobial resistance

KW - Carbapenem

KW - Insertion sequence (IS)

UR - https://www.scopus.com/pages/publications/84925363165

U2 - 10.4167/jbv.2015.45.1.51

DO - 10.4167/jbv.2015.45.1.51

M3 - Article

AN - SCOPUS:84925363165

SN - 1598-2467

VL - 45

SP - 51

EP - 53

JO - Journal of Bacteriology and Virology

JF - Journal of Bacteriology and Virology

IS - 1

ER -

ISAba15 inserted into outer membrane protein gene carO in Acinetobacter baumannii

Abstract

Keywords

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