Intracytoplasmic sperm injection may lead to vertical transmission, expansion, and de novo occurrence of Y-chromosome microdeletions in male fetuses

  • Sook Hwan Lee
  • , So Yeon Ahn
  • , Kyo Won Lee
  • , Kyu Bum Kwack
  • , Hye Sun Jun
  • , Kwang Yul Cha

Research output: Contribution to journalArticlepeer-review

Abstract

Y-chromosome microdeletion in male fetuses conceived by intracytoplasmic sperm injection (ICSI) was screened by polymerase chain reaction for sequence-tagged sites in azoospermia factor (AZF)-b and AZFc regions. Treatment with ICSI may lead to vertical transmission, expansion, and de novo Y-chromosome microdeletion in male fetuses.

Original languageEnglish
Pages (from-to)1512-1515
Number of pages4
JournalFertility and Sterility
Volume85
Issue number5
DOIs
StatePublished - May 2006

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