In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile

Ho Jae Han; Jaeyoon John Kim; Danielle Pyne; Anthea Travas; Amirthagowri Ambalavanan; Shinya Kimura; Michael W. Deininger; Jong Won Kim; Dennis Dong Hwan Kim

doi:10.1038/s41375-023-02122-5

In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile

Ho Jae Han
, Jaeyoon John Kim
, Danielle Pyne
, Anthea Travas
, Amirthagowri Ambalavanan
, Shinya Kimura
, Michael W. Deininger
, Jong Won Kim
, Dennis Dong Hwan Kim

Department of Laboratory Medicine and Genetics

Sungkyunkwan University
Princess Margaret Cancer Centre
Saga University
Versiti

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Original language	English
Pages (from-to)	412-415
Number of pages	4
Journal	Leukemia
Volume	38
Issue number	2
DOIs	https://doi.org/10.1038/s41375-023-02122-5
State	Published - Feb 2024

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Han, H. J., Kim, J. J., Pyne, D., Travas, A., Ambalavanan, A., Kimura, S., Deininger, M. W., Kim, J. W., & Kim, D. D. H. (2024). In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile. Leukemia, 38(2), 412-415. https://doi.org/10.1038/s41375-023-02122-5

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title = "In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile",

author = "Han, \{Ho Jae\} and Kim, \{Jaeyoon John\} and Danielle Pyne and Anthea Travas and Amirthagowri Ambalavanan and Shinya Kimura and Deininger, \{Michael W.\} and Kim, \{Jong Won\} and Kim, \{Dennis Dong Hwan\}",

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Han, HJ, Kim, JJ, Pyne, D, Travas, A, Ambalavanan, A, Kimura, S, Deininger, MW, Kim, JW & Kim, DDH 2024, 'In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile', Leukemia, vol. 38, no. 2, pp. 412-415. https://doi.org/10.1038/s41375-023-02122-5

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T1 - In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile

AU - Han, Ho Jae

AU - Kim, Jaeyoon John

AU - Pyne, Danielle

AU - Travas, Anthea

AU - Ambalavanan, Amirthagowri

AU - Kimura, Shinya

AU - Deininger, Michael W.

AU - Kim, Jong Won

AU - Kim, Dennis Dong Hwan

PY - 2024/2

Y1 - 2024/2

UR - https://www.scopus.com/pages/publications/85180657662

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DO - 10.1038/s41375-023-02122-5

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AN - SCOPUS:85180657662

SN - 0887-6924

VL - 38

SP - 412

EP - 415

JO - Leukemia

JF - Leukemia

IS - 2

ER -

In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile

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