Highly responsive hydrogel scaffolds formed by three-dimensional organization of microgel nanoparticles

  • Eun Chul Cho
  • , Jin Woong Kim
  • , Alberto Fernández-Nieves
  • , David A. Weitz

Research output: Contribution to journalArticlepeer-review

142 Scopus citations

Abstract

We present a robust and straightforward method for fabricating remarkably responsive hydrogel scaffolds consisting of submicron-sized microgel particles. We demonstrate that the microgel particles assemble either through bridging or depletion interactions to yield a structure that swells or deswells at a macroscopic level in much shorter times as compared to a bulk polymer gel of similar characteristics. This approach offers a new way of fabricating functional hydrogel scaffolds with controllable responsiveness to applied stimuli and excellent loading capability for a wide variety of materials, irrespective of chemistry, size, and shape.

Original languageEnglish
Pages (from-to)168-172
Number of pages5
JournalNano Letters
Volume8
Issue number1
DOIs
StatePublished - Jan 2008
Externally publishedYes

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