Abstract
A technique on high frame rate(28fps), high frequency coregistered ultrasound and photoacoustic imaging for visualizing zebrafish heart blood flow was demonstrated. This approach was achieved with a 40MHz light weight(0.38g) ring-type transducer, serving as the ultrasound transmitter and receiver, to allow an optic fiber, coupled with a 532nm laser, to be inserted into the hole. From the wire target study, axial resolutions of 38μm and 42μm were obtained for ultrasound and photoacoustic imaging, respectively. Carbon nanotubes were utilized as contrast agents to increase the flow signal level by 20dB in phantom studies, and zebrafish heart blood flow was successfully observed.
| Original language | English |
|---|---|
| Pages (from-to) | 14636-14642 |
| Number of pages | 7 |
| Journal | Optics Express |
| Volume | 21 |
| Issue number | 12 |
| DOIs | |
| State | Published - Jun 2013 |
| Externally published | Yes |
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