Genetic diversity of Legionella pneumophila inferred from rpoB and dotA sequences

K. S. Ko; H. Miyamoto; H. K. Lee; M. Y. Park; K. Fukuda; B. J. Park; Y. H. Kook

doi:10.1111/j.1469-0691.2005.01338.x

Genetic diversity of Legionella pneumophila inferred from rpoB and dotA sequences

K. S. Ko
, H. Miyamoto
, H. K. Lee
, M. Y. Park
, K. Fukuda
, B. J. Park
, Y. H. Kook

Seoul National University
University of Occupational and Environmental Health, Japan
Korea National Institute of Health

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

This study characterised the population structure of Legionella pneumophila by comparing the rpoB (300-bp) and dotA (360-bp) sequences of 267 isolates (18 reference strains, 149 Korean isolates and 100 Japanese isolates). In addition to the six clonal subgroups established previously, four subgroups, P-V to P-VIII, were identified. Subgroupings based on rpoB and dotA sequences were found to correlate with the source of the isolates, and this data may be useful for future epidemiological studies. Fourteen (five Korean and nine Japanese) isolates showed incongruent subgroupings in the rpoB and dotA trees, suggesting that genetic exchange among subgroups, and even among subspecies, may occur frequently in nature.

Original language	English
Pages (from-to)	254-261
Number of pages	8
Journal	Clinical Microbiology and Infection
Volume	12
Issue number	3
DOIs	https://doi.org/10.1111/j.1469-0691.2005.01338.x
State	Published - Mar 2006
Externally published	Yes

Keywords

Legionella pneumophila
Population structure
Sequence analysis
Subgroup
dotA
rpoB

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10.1111/j.1469-0691.2005.01338.x

Cite this

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title = "Genetic diversity of Legionella pneumophila inferred from rpoB and dotA sequences",

abstract = "This study characterised the population structure of Legionella pneumophila by comparing the rpoB (300-bp) and dotA (360-bp) sequences of 267 isolates (18 reference strains, 149 Korean isolates and 100 Japanese isolates). In addition to the six clonal subgroups established previously, four subgroups, P-V to P-VIII, were identified. Subgroupings based on rpoB and dotA sequences were found to correlate with the source of the isolates, and this data may be useful for future epidemiological studies. Fourteen (five Korean and nine Japanese) isolates showed incongruent subgroupings in the rpoB and dotA trees, suggesting that genetic exchange among subgroups, and even among subspecies, may occur frequently in nature.",

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T1 - Genetic diversity of Legionella pneumophila inferred from rpoB and dotA sequences

AU - Ko, K. S.

AU - Miyamoto, H.

AU - Lee, H. K.

AU - Park, M. Y.

AU - Fukuda, K.

AU - Park, B. J.

AU - Kook, Y. H.

PY - 2006/3

Y1 - 2006/3

N2 - This study characterised the population structure of Legionella pneumophila by comparing the rpoB (300-bp) and dotA (360-bp) sequences of 267 isolates (18 reference strains, 149 Korean isolates and 100 Japanese isolates). In addition to the six clonal subgroups established previously, four subgroups, P-V to P-VIII, were identified. Subgroupings based on rpoB and dotA sequences were found to correlate with the source of the isolates, and this data may be useful for future epidemiological studies. Fourteen (five Korean and nine Japanese) isolates showed incongruent subgroupings in the rpoB and dotA trees, suggesting that genetic exchange among subgroups, and even among subspecies, may occur frequently in nature.

AB - This study characterised the population structure of Legionella pneumophila by comparing the rpoB (300-bp) and dotA (360-bp) sequences of 267 isolates (18 reference strains, 149 Korean isolates and 100 Japanese isolates). In addition to the six clonal subgroups established previously, four subgroups, P-V to P-VIII, were identified. Subgroupings based on rpoB and dotA sequences were found to correlate with the source of the isolates, and this data may be useful for future epidemiological studies. Fourteen (five Korean and nine Japanese) isolates showed incongruent subgroupings in the rpoB and dotA trees, suggesting that genetic exchange among subgroups, and even among subspecies, may occur frequently in nature.

KW - Legionella pneumophila

KW - Population structure

KW - Sequence analysis

KW - Subgroup

KW - dotA

KW - rpoB

UR - https://www.scopus.com/pages/publications/33644884486

U2 - 10.1111/j.1469-0691.2005.01338.x

DO - 10.1111/j.1469-0691.2005.01338.x

M3 - Article

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AN - SCOPUS:33644884486

SN - 1198-743X

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SP - 254

EP - 261

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

IS - 3

ER -

Genetic diversity of Legionella pneumophila inferred from rpoB and dotA sequences

Abstract

Keywords

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