Focal increased ¹⁸F FP-CIT uptake in a recent ischemic lesion in the frontal lobe

A 65-year-old male patient was referred for rapid functional decline over 1 month with dysphagia and dysarthria. Past history disclosed left side weakness for 5 years. ¹⁸F FP-CIT PET/CT was performed to evaluate the possibility of pseudobulbar palsy. Images showed a defect in the right posterior putamen that was consistent with an old cerebral infarction lesion. Unexpectedly, an oval area of intense ¹⁸F FP-CIT uptake was found in the left frontal lobe. MRI and ¹⁸F-FDG PET/CT indicated the lesion to be caused by recent cerebral ischemia.