Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

Yong Jun Choi; Yae Jean Kim; Dongeun Yong; Jung Hyun Byun; Taek Soo Kim; Yun Sil Chang; Min Ji Choi; Seung Ah Byeon; Eun Jeong Won; Soo Hyun Kim; Myung Geun Shin; Jong Hee Shin

doi:10.3201/eid2409.180625

Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

Yong Jun Choi
, Yae Jean Kim
, Dongeun Yong
, Jung Hyun Byun
, Taek Soo Kim
, Yun Sil Chang
, Min Ji Choi
, Seung Ah Byeon
, Eun Jeong Won
, Soo Hyun Kim
, Myung Geun Shin
, Jong Hee Shin

Chonnam National University
Sungkyunkwan University
Yonsei University
Seoul National University

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.

Original language	English
Pages (from-to)	1768-1770
Number of pages	3
Journal	Emerging Infectious Diseases
Volume	24
Issue number	9
DOIs	https://doi.org/10.3201/eid2409.180625
State	Published - Sep 2018
Externally published	Yes

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10.3201/eid2409.180625

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title = "Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea",

abstract = "We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.",

author = "Choi, \{Yong Jun\} and Kim, \{Yae Jean\} and Dongeun Yong and Byun, \{Jung Hyun\} and Kim, \{Taek Soo\} and Chang, \{Yun Sil\} and Choi, \{Min Ji\} and Byeon, \{Seung Ah\} and Won, \{Eun Jeong\} and Kim, \{Soo Hyun\} and Shin, \{Myung Geun\} and Shin, \{Jong Hee\}",

year = "2018",

month = sep,

doi = "10.3201/eid2409.180625",

language = "English",

volume = "24",

pages = "1768--1770",

journal = "Emerging Infectious Diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

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TY - JOUR

T1 - Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

AU - Choi, Yong Jun

AU - Kim, Yae Jean

AU - Yong, Dongeun

AU - Byun, Jung Hyun

AU - Kim, Taek Soo

AU - Chang, Yun Sil

AU - Choi, Min Ji

AU - Byeon, Seung Ah

AU - Won, Eun Jeong

AU - Kim, Soo Hyun

AU - Shin, Myung Geun

AU - Shin, Jong Hee

PY - 2018/9

Y1 - 2018/9

N2 - We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.

AB - We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.

UR - https://www.scopus.com/pages/publications/85052192895

U2 - 10.3201/eid2409.180625

DO - 10.3201/eid2409.180625

M3 - Article

C2 - 30124412

AN - SCOPUS:85052192895

SN - 1080-6040

VL - 24

SP - 1768

EP - 1770

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 9

ER -

Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

Abstract

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