Flavonoids from Symplocos racemosa

Mila Jung; Janggyoo Choi; Hee Sung Chae; Jae Youl Cho; Young Dong Kim; Khin Myo Htwe; Woo Shin Lee; Young Won Chin; Jinwoong Kim; Kee Dong Yoon

doi:10.3390/molecules20010358

Flavonoids from Symplocos racemosa

Mila Jung, Janggyoo Choi, Hee Sung Chae, Jae Youl Cho, Young Dong Kim, Khin Myo Htwe, Woo Shin Lee, Young Won Chin, Jinwoong Kim, Kee Dong Yoon

Department of Integrative Biotechnology

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A novel isoflavone glycoside, peseudobatigenin 7- O-[β-D-apiofuranosyl-(1''''→5''')-O-β-D-apiofuranosyl-(1'''→6'')]-β- D-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.

Original language	English
Pages (from-to)	358-365
Number of pages	8
Journal	Molecules
Volume	20
Issue number	1
DOIs	https://doi.org/10.3390/molecules20010358
State	Published - 1 Jan 2015

Keywords

Flavonoids
Symplocos racemosa
Sympracemoside

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10.3390/molecules20010358

Cite this

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title = "Flavonoids from Symplocos racemosa",

abstract = "A novel isoflavone glycoside, peseudobatigenin 7- O-[β-D-apiofuranosyl-(1''''→5''')-O-β-D-apiofuranosyl-(1'''→6'')]-β- D-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.",

keywords = "Flavonoids, Symplocos racemosa, Sympracemoside",

author = "Mila Jung and Janggyoo Choi and Chae, \{Hee Sung\} and Cho, \{Jae Youl\} and Kim, \{Young Dong\} and Htwe, \{Khin Myo\} and Lee, \{Woo Shin\} and Chin, \{Young Won\} and Jinwoong Kim and Yoon, \{Kee Dong\}",

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year = "2015",

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doi = "10.3390/molecules20010358",

language = "English",

volume = "20",

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T1 - Flavonoids from Symplocos racemosa

AU - Jung, Mila

AU - Choi, Janggyoo

AU - Chae, Hee Sung

AU - Cho, Jae Youl

AU - Kim, Young Dong

AU - Htwe, Khin Myo

AU - Lee, Woo Shin

AU - Chin, Young Won

AU - Kim, Jinwoong

AU - Yoon, Kee Dong

PY - 2015/1/1

Y1 - 2015/1/1

N2 - A novel isoflavone glycoside, peseudobatigenin 7- O-[β-D-apiofuranosyl-(1''''→5''')-O-β-D-apiofuranosyl-(1'''→6'')]-β- D-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.

AB - A novel isoflavone glycoside, peseudobatigenin 7- O-[β-D-apiofuranosyl-(1''''→5''')-O-β-D-apiofuranosyl-(1'''→6'')]-β- D-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.

KW - Flavonoids

KW - Symplocos racemosa

KW - Sympracemoside

UR - https://www.scopus.com/pages/publications/84921496843

U2 - 10.3390/molecules20010358

DO - 10.3390/molecules20010358

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AN - SCOPUS:84921496843

SN - 1420-3049

VL - 20

SP - 358

EP - 365

JO - Molecules

JF - Molecules

IS - 1

ER -

Flavonoids from Symplocos racemosa

Abstract

Keywords

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