Flavonoids from Symplocos racemosa

Mila Jung; Janggyoo Choi; Hee Sung Chae; Jae Youl Cho; Young Dong Kim; Khin Myo Htwe; Woo Shin Lee; Young Won Chin; Jinwoong Kim; Kee Dong Yoon

doi:10.3390/molecules20010358

Flavonoids from Symplocos racemosa

Mila Jung
, Janggyoo Choi
, Hee Sung Chae
, Jae Youl Cho
, Young Dong Kim
, Khin Myo Htwe
, Woo Shin Lee
, Young Won Chin
, Jinwoong Kim
, Kee Dong Yoon

Department of Integrative Biotechnology

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

A novel isoflavone glycoside, peseudobatigenin 7- O-[β-D-apiofuranosyl-(1''''→5''')-O-β-D-apiofuranosyl-(1'''→6'')]-β- D-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.

Original language	English
Pages (from-to)	358-365
Number of pages	8
Journal	Molecules
Volume	20
Issue number	1
DOIs	https://doi.org/10.3390/molecules20010358
State	Published - 1 Jan 2015

Keywords

Flavonoids
Symplocos racemosa
Sympracemoside

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10.3390/molecules20010358

Cite this

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title = "Flavonoids from Symplocos racemosa",

abstract = "A novel isoflavone glycoside, peseudobatigenin 7- O-[β-D-apiofuranosyl-(1''''→5''')-O-β-D-apiofuranosyl-(1'''→6'')]-β- D-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.",

keywords = "Flavonoids, Symplocos racemosa, Sympracemoside",

author = "Mila Jung and Janggyoo Choi and Chae, \{Hee Sung\} and Cho, \{Jae Youl\} and Kim, \{Young Dong\} and Htwe, \{Khin Myo\} and Lee, \{Woo Shin\} and Chin, \{Young Won\} and Jinwoong Kim and Yoon, \{Kee Dong\}",

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year = "2015",

month = jan,

day = "1",

doi = "10.3390/molecules20010358",

language = "English",

volume = "20",

pages = "358--365",

journal = "Molecules",

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TY - JOUR

T1 - Flavonoids from Symplocos racemosa

AU - Jung, Mila

AU - Choi, Janggyoo

AU - Chae, Hee Sung

AU - Cho, Jae Youl

AU - Kim, Young Dong

AU - Htwe, Khin Myo

AU - Lee, Woo Shin

AU - Chin, Young Won

AU - Kim, Jinwoong

AU - Yoon, Kee Dong

PY - 2015/1/1

Y1 - 2015/1/1

N2 - A novel isoflavone glycoside, peseudobatigenin 7- O-[β-D-apiofuranosyl-(1''''→5''')-O-β-D-apiofuranosyl-(1'''→6'')]-β- D-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.

AB - A novel isoflavone glycoside, peseudobatigenin 7- O-[β-D-apiofuranosyl-(1''''→5''')-O-β-D-apiofuranosyl-(1'''→6'')]-β- D-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.

KW - Flavonoids

KW - Symplocos racemosa

KW - Sympracemoside

UR - https://www.scopus.com/pages/publications/84921496843

U2 - 10.3390/molecules20010358

DO - 10.3390/molecules20010358

M3 - Article

C2 - 25549060

AN - SCOPUS:84921496843

SN - 1420-3049

VL - 20

SP - 358

EP - 365

JO - Molecules

JF - Molecules

IS - 1

ER -

Flavonoids from Symplocos racemosa

Abstract

Keywords

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