Fabrication of m13-bacteriophage-conjugated alginate scaffold for hard tissue engineering

Jaeyoon Lee, Jiun Lee, Soo Jung Chae, Wonjin Kim, Miji Yeo, Geunhyung Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Statement of Purpose: Alginate is commonly used biocompatible polysaccharide which has good biocompatibility, hydrophilicity, non-antigenicity, easy/rapid gelation using calcium ions, and controllable biodegradability [1]. However, as reported by several groups, it has no cell-activating sites and has low mechanical properties for hard tissue regeneration. To overcome these issues, we fabricate the chemically conjugated M13 bacteriophage/alginate scaffold using the low temperature (-20℃) printing process. Through this bioprinting process we could produce biologically improved 3D scaffold for bone tissue regeneration.

Original languageEnglish
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Pages886
Number of pages1
ISBN (Electronic)9781510883901
StatePublished - 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: 3 Apr 20196 Apr 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Country/TerritoryUnited States
CitySeattle
Period3/04/196/04/19

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