TY - JOUR
T1 - Eye-Preserving Surgery Followed by Adjuvant Radiotherapy for Lacrimal Gland Carcinoma
T2 - Outcomes in 37 Patients
AU - Woo, Kyung In
AU - Sagiv, Oded
AU - Han, Jisang
AU - Frank, Steven J.
AU - Kim, Yoon Duck
AU - Esmaeli, Bita
N1 - Publisher Copyright:
© 2018 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Purpose: To describe the clinical outcomes of eye-preserving surgery followed by adjuvant radiotherapy in patients with lacrimal gland carcinoma. Methods: Thirty-seven patients with lacrimal gland carcinoma who underwent eye-preserving surgery were studied. Results: At last follow up, 32 patients were alive without disease, 3 patients were alive with disease with distant metastasis, 1 patient had died of disease, and 1 patient had died of other cause. The 5-year recurrence-free survival rate was worse in patients without than in patients with adjuvant radiotherapy (p = 0.001) and worse in patients with T3-T4 tumors than in patients with T1-T2 tumors (p = 0.027). At last follow up, 25 patients (68%) had visual acuity of 20/40 or better. Conclusions: In patients with lacrimal gland carcinoma, eye-preserving surgery and adjuvant radiotherapy is associated with reasonable local control rates and visual and ocular function. Postoperative adjuvant radiotherapy seems to enhance local control rates.
AB - Purpose: To describe the clinical outcomes of eye-preserving surgery followed by adjuvant radiotherapy in patients with lacrimal gland carcinoma. Methods: Thirty-seven patients with lacrimal gland carcinoma who underwent eye-preserving surgery were studied. Results: At last follow up, 32 patients were alive without disease, 3 patients were alive with disease with distant metastasis, 1 patient had died of disease, and 1 patient had died of other cause. The 5-year recurrence-free survival rate was worse in patients without than in patients with adjuvant radiotherapy (p = 0.001) and worse in patients with T3-T4 tumors than in patients with T1-T2 tumors (p = 0.027). At last follow up, 25 patients (68%) had visual acuity of 20/40 or better. Conclusions: In patients with lacrimal gland carcinoma, eye-preserving surgery and adjuvant radiotherapy is associated with reasonable local control rates and visual and ocular function. Postoperative adjuvant radiotherapy seems to enhance local control rates.
UR - https://www.scopus.com/pages/publications/85052512556
U2 - 10.1097/IOP.0000000000001106
DO - 10.1097/IOP.0000000000001106
M3 - Article
C2 - 29634603
AN - SCOPUS:85052512556
SN - 0740-9303
VL - 34
SP - 570
EP - 574
JO - Ophthalmic Plastic and Reconstructive Surgery
JF - Ophthalmic Plastic and Reconstructive Surgery
IS - 6
ER -
