Evaluation of forensic genetic parameters of 12 STR loci in the Korean population using the InvestigatorⓇ HDplex kit

Ju Yeon Jung; Eun Hye Kim; Yu Li Oh; Hyun Chul Park; Jung Ho Hwang; Si Keun Lim

doi:10.1007/s00414-017-1592-8

Evaluation of forensic genetic parameters of 12 STR loci in the Korean population using the Investigator^Ⓡ HDplex kit

Ju Yeon Jung, Eun Hye Kim, Yu Li Oh, Hyun Chul Park, Jung Ho Hwang, Si Keun Lim

National Forensic Service

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

We genotyped and calculated the forensic parameters of 10 non-CODIS loci and 2 CODIS loci of 990 Korean individuals using the Investigator^Ⓡ HDplex kit. No significant deviations from Hardy–Weinberg equilibrium (after Bonferroni correction for multiple testing) or genetic linkage disequilibrium were observed. The calculated matching probability and power of discrimination ranged from 0.0080 to 0.2014, and 0.7986 to 0.9920, respectively. We conclude that the markers of the kit are highly informative corroborative tools for forensic DNA analysis.

Original language	English
Pages (from-to)	1247-1249
Number of pages	3
Journal	International journal of legal medicine
Volume	131
Issue number	5
DOIs	https://doi.org/10.1007/s00414-017-1592-8
State	Published - 1 Sep 2017
Externally published	Yes

Keywords

Forensic genetic parameters
Investigator HDplex kit
Korean population

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10.1007/s00414-017-1592-8

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title = "Evaluation of forensic genetic parameters of 12 STR loci in the Korean population using the InvestigatorⓇ HDplex kit",

abstract = "We genotyped and calculated the forensic parameters of 10 non-CODIS loci and 2 CODIS loci of 990 Korean individuals using the InvestigatorⓇ HDplex kit. No significant deviations from Hardy–Weinberg equilibrium (after Bonferroni correction for multiple testing) or genetic linkage disequilibrium were observed. The calculated matching probability and power of discrimination ranged from 0.0080 to 0.2014, and 0.7986 to 0.9920, respectively. We conclude that the markers of the kit are highly informative corroborative tools for forensic DNA analysis.",

keywords = "Forensic genetic parameters, Investigator HDplex kit, Korean population",

author = "Jung, \{Ju Yeon\} and Kim, \{Eun Hye\} and Oh, \{Yu Li\} and Park, \{Hyun Chul\} and Hwang, \{Jung Ho\} and Lim, \{Si Keun\}",

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doi = "10.1007/s00414-017-1592-8",

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AU - Jung, Ju Yeon

AU - Kim, Eun Hye

AU - Oh, Yu Li

AU - Park, Hyun Chul

AU - Hwang, Jung Ho

AU - Lim, Si Keun

PY - 2017/9/1

Y1 - 2017/9/1

N2 - We genotyped and calculated the forensic parameters of 10 non-CODIS loci and 2 CODIS loci of 990 Korean individuals using the InvestigatorⓇ HDplex kit. No significant deviations from Hardy–Weinberg equilibrium (after Bonferroni correction for multiple testing) or genetic linkage disequilibrium were observed. The calculated matching probability and power of discrimination ranged from 0.0080 to 0.2014, and 0.7986 to 0.9920, respectively. We conclude that the markers of the kit are highly informative corroborative tools for forensic DNA analysis.

AB - We genotyped and calculated the forensic parameters of 10 non-CODIS loci and 2 CODIS loci of 990 Korean individuals using the InvestigatorⓇ HDplex kit. No significant deviations from Hardy–Weinberg equilibrium (after Bonferroni correction for multiple testing) or genetic linkage disequilibrium were observed. The calculated matching probability and power of discrimination ranged from 0.0080 to 0.2014, and 0.7986 to 0.9920, respectively. We conclude that the markers of the kit are highly informative corroborative tools for forensic DNA analysis.

KW - Forensic genetic parameters

KW - Investigator HDplex kit

KW - Korean population

UR - https://www.scopus.com/pages/publications/85017458368

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JO - International journal of legal medicine

JF - International journal of legal medicine

IS - 5

ER -

Evaluation of forensic genetic parameters of 12 STR loci in the Korean population using the Investigator^Ⓡ HDplex kit

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Keywords

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