Electrochemical nanoneedle biosensor based on multiwall carbon nanotube

  • Hankil Boo
  • , Ran A. Jeong
  • , Sejin Park
  • , Keun Soo Kim
  • , Kay Hyeok An
  • , Young Hee Lee
  • , Ji Hyung Han
  • , Hee Chan Kim
  • , Taek Dong Chung

Research output: Contribution to journalArticlepeer-review

104 Scopus citations

Abstract

We report the fabrication and analytical functions of a biosensor based on a nanoneedle consisting of a multiwall carbon nanotube attached to the end of an etched tungsten tip. The devised electrode is the smallest needle-type biosensor reported to date. The nanoneedles prepared in this work are 30 nm in diameter and 2-3 μm in length. Dopamine and glutamate, which are physiologically important neurotransmitters, were successfully detected using these nanoneedles. Bare nanoneedles detected dopamine in the range from 100 to 1000 μM by differential pulse voltammetry, and enzyme-modified nanoneedles were able to respond to glutamate in the 100-500 μM range by potentiostatic amperometry.

Original languageEnglish
Pages (from-to)617-620
Number of pages4
JournalAnalytical Chemistry
Volume78
Issue number2
DOIs
StatePublished - 15 Jan 2006

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