Effects of laparoscopic surgery on serum anti-mllerian hormone levels in reproductive-aged women with endometrioma

Dong Yun Lee, Na Young Kim, Min Jae Kim, Byung Koo Yoon, Dooseok Choi

Research output: Contribution to journalArticlepeer-review

72 Scopus citations

Abstract

A few studies have investigated the effects of laparoscopic cystectomy for endometrioma on ovarian reserve using serum anti-Mllerian hormone (AMH) levels and have shown inconsistent results. This prospective study was performed to estimate early changes in serum AMH after laparoscopic surgery for endometrioma. In 27 women aged 2146 years who underwent laparoscopic unilateral cystectomy (n = 13) or oophorectomy (n = 14) for endometrioma, we measured pre- and postoperative serum AMH levels at baseline and 1 week, 1 month, and 3 months after surgery. Serial changes in serum AMH levels were analyzed according to the operation type using analysis of variance. Mean levels of serum AMH decreased significantly immediately after surgery and remained for up to 3 months in both operation types (P = 0.002 for cystectomy group and P <0.001 for oophorectomy group). In addition, the serum AMH levels showed similar patterns of change after cystectomy or oophorectomy. In conclusion, laparoscopic ovarian cystectomy for endometrioma appears to decrease serum AMH levels immediately after surgery.

Original languageEnglish
Pages (from-to)733-736
Number of pages4
JournalGynecological Endocrinology
Volume27
Issue number10
DOIs
StatePublished - Oct 2011

Keywords

  • Anti-Mllerian hormone
  • endometrioma
  • laparoscopy
  • ovarian reserve

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