Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites

Hye Jung Jang; Sung Bin Park; Tarek M. Bedair; Min Kyu Oh; Dong June Ahn; Wooram Park; Yoon Ki Joung; Dong Keun Han

doi:10.1016/j.jiec.2017.10.032

Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites

Hye Jung Jang
, Sung Bin Park
, Tarek M. Bedair
, Min Kyu Oh
, Dong June Ahn
, Wooram Park
, Yoon Ki Joung
, Dong Keun Han

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Five different shapes of magnesium hydroxide (Mg(OH)₂) particles (Plate-S, Plate-N, Disk, Whisker, and Fiber) were synthesized and added to biopolymer (i.e., Poly(lactic-co-glycolic acid) (PLGA)) composite to improve their mechanical and biological properties. The PLGA composite films including Mg(OH)₂ particles were prepared by a solvent casting method. Their mechanical and biological properties were compared according to the composites containing different shapes of Mg(OH)₂ particles. Among them, the fiber shape of Mg(OH)₂ provided the highest mechanical strength, and anti-inflammation and anti-bacterial activity to PLGA films among other forms. This study demonstrated a new strategy for the design of biomaterials by controlling the form of inorganic additives.

Original language	English
Pages (from-to)	266-276
Number of pages	11
Journal	Journal of Industrial and Engineering Chemistry
Volume	59
DOIs	https://doi.org/10.1016/j.jiec.2017.10.032
State	Published - 25 Mar 2018
Externally published	Yes

Keywords

Anti-bacterial activity
Anti-inflammation effect
Magnesium hydroxide
Mechanical property
Poly(lactic-co-glycolic acid) composites

Access to Document

10.1016/j.jiec.2017.10.032

Cite this

@article{714f62f6f0124dcd87c60b45a41291f1,

title = "Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites",

abstract = "Five different shapes of magnesium hydroxide (Mg(OH)2) particles (Plate-S, Plate-N, Disk, Whisker, and Fiber) were synthesized and added to biopolymer (i.e., Poly(lactic-co-glycolic acid) (PLGA)) composite to improve their mechanical and biological properties. The PLGA composite films including Mg(OH)2 particles were prepared by a solvent casting method. Their mechanical and biological properties were compared according to the composites containing different shapes of Mg(OH)2 particles. Among them, the fiber shape of Mg(OH)2 provided the highest mechanical strength, and anti-inflammation and anti-bacterial activity to PLGA films among other forms. This study demonstrated a new strategy for the design of biomaterials by controlling the form of inorganic additives.",

keywords = "Anti-bacterial activity, Anti-inflammation effect, Magnesium hydroxide, Mechanical property, Poly(lactic-co-glycolic acid) composites",

author = "Jang, \{Hye Jung\} and Park, \{Sung Bin\} and Bedair, \{Tarek M.\} and Oh, \{Min Kyu\} and Ahn, \{Dong June\} and Wooram Park and Joung, \{Yoon Ki\} and Han, \{Dong Keun\}",

note = "Publisher Copyright: {\textcopyright} 2017 The Korean Society of Industrial and Engineering Chemistry",

year = "2018",

month = mar,

day = "25",

doi = "10.1016/j.jiec.2017.10.032",

language = "English",

volume = "59",

pages = "266--276",

journal = "Journal of Industrial and Engineering Chemistry",

issn = "1226-086X",

publisher = "Korean Society of Industrial Engineering Chemistry",

}

TY - JOUR

T1 - Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites

AU - Jang, Hye Jung

AU - Park, Sung Bin

AU - Bedair, Tarek M.

AU - Oh, Min Kyu

AU - Ahn, Dong June

AU - Park, Wooram

AU - Joung, Yoon Ki

AU - Han, Dong Keun

PY - 2018/3/25

Y1 - 2018/3/25

N2 - Five different shapes of magnesium hydroxide (Mg(OH)2) particles (Plate-S, Plate-N, Disk, Whisker, and Fiber) were synthesized and added to biopolymer (i.e., Poly(lactic-co-glycolic acid) (PLGA)) composite to improve their mechanical and biological properties. The PLGA composite films including Mg(OH)2 particles were prepared by a solvent casting method. Their mechanical and biological properties were compared according to the composites containing different shapes of Mg(OH)2 particles. Among them, the fiber shape of Mg(OH)2 provided the highest mechanical strength, and anti-inflammation and anti-bacterial activity to PLGA films among other forms. This study demonstrated a new strategy for the design of biomaterials by controlling the form of inorganic additives.

AB - Five different shapes of magnesium hydroxide (Mg(OH)2) particles (Plate-S, Plate-N, Disk, Whisker, and Fiber) were synthesized and added to biopolymer (i.e., Poly(lactic-co-glycolic acid) (PLGA)) composite to improve their mechanical and biological properties. The PLGA composite films including Mg(OH)2 particles were prepared by a solvent casting method. Their mechanical and biological properties were compared according to the composites containing different shapes of Mg(OH)2 particles. Among them, the fiber shape of Mg(OH)2 provided the highest mechanical strength, and anti-inflammation and anti-bacterial activity to PLGA films among other forms. This study demonstrated a new strategy for the design of biomaterials by controlling the form of inorganic additives.

KW - Anti-bacterial activity

KW - Anti-inflammation effect

KW - Magnesium hydroxide

KW - Mechanical property

KW - Poly(lactic-co-glycolic acid) composites

UR - https://www.scopus.com/pages/publications/85034447916

U2 - 10.1016/j.jiec.2017.10.032

DO - 10.1016/j.jiec.2017.10.032

M3 - Article

AN - SCOPUS:85034447916

SN - 1226-086X

VL - 59

SP - 266

EP - 276

JO - Journal of Industrial and Engineering Chemistry

JF - Journal of Industrial and Engineering Chemistry

ER -

Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this