Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

A. Zer; M. J. Ahn; F. Barlesi; L. Bubendorf; D. De Ruysscher; P. Garrido; O. Gautschi; L. E. Hendriks; P. A. Jänne; K. M. Kerr; C. Mascaux; T. Mitsudomi; S. Peters; C. Rolfo; A. Sacher; S. Senan; P. Ugalde; N. B. Leighl

doi:10.1016/j.annonc.2025.08.003

Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

A. Zer
, M. J. Ahn
, F. Barlesi
, L. Bubendorf
, D. De Ruysscher
, P. Garrido
, O. Gautschi
, L. E. Hendriks
, P. A. Jänne
, K. M. Kerr
, C. Mascaux
, T. Mitsudomi
, S. Peters
, C. Rolfo
, A. Sacher
, S. Senan
, P. Ugalde
, N. B. Leighl

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

•This ESMO Clinical Practice Guideline provides key recommendations for managing early and locally advanced NSCLC. •The guideline covers diagnosis, staging, risk assessment, treatment and follow-up. •Treatment algorithms for resectable and unresectable disease are provided. •The authors encompass a multidisciplinary group of experts from different institutions and countries. •Recommendations are based on available scientific data and the authors’ collective expert opinion.

Original language	English
Journal	Annals of Oncology
DOIs	https://doi.org/10.1016/j.annonc.2025.08.003
State	Accepted/In press - 2025

Keywords

diagnosis
early non-small-cell lung cancer (NSCLC)
guideline
staging
treatment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.annonc.2025.08.003

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Zer, A., Ahn, M. J., Barlesi, F., Bubendorf, L., De Ruysscher, D., Garrido, P., Gautschi, O., Hendriks, L. E., Jänne, P. A., Kerr, K. M., Mascaux, C., Mitsudomi, T., Peters, S., Rolfo, C., Sacher, A., Senan, S., Ugalde, P., & Leighl, N. B. (Accepted/In press). Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology. https://doi.org/10.1016/j.annonc.2025.08.003

@article{01d4cc3e9eea494fbe740c10bf31c3b3,

title = "Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up",

abstract = "•This ESMO Clinical Practice Guideline provides key recommendations for managing early and locally advanced NSCLC. •The guideline covers diagnosis, staging, risk assessment, treatment and follow-up. •Treatment algorithms for resectable and unresectable disease are provided. •The authors encompass a multidisciplinary group of experts from different institutions and countries. •Recommendations are based on available scientific data and the authors{\textquoteright} collective expert opinion.",

keywords = "diagnosis, early non-small-cell lung cancer (NSCLC), guideline, staging, treatment",

author = "A. Zer and Ahn, \{M. J.\} and F. Barlesi and L. Bubendorf and \{De Ruysscher\}, D. and P. Garrido and O. Gautschi and Hendriks, \{L. E.\} and J{\"a}nne, \{P. A.\} and Kerr, \{K. M.\} and C. Mascaux and T. Mitsudomi and S. Peters and C. Rolfo and A. Sacher and S. Senan and P. Ugalde and Leighl, \{N. B.\}",

note = "Publisher Copyright: {\textcopyright} 2025 European Society for Medical Oncology. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.",

year = "2025",

doi = "10.1016/j.annonc.2025.08.003",

language = "English",

journal = "Annals of Oncology",

issn = "0923-7534",

publisher = "Elsevier Ltd",

}

Zer, A, Ahn, MJ, Barlesi, F, Bubendorf, L, De Ruysscher, D, Garrido, P, Gautschi, O, Hendriks, LE, Jänne, PA, Kerr, KM, Mascaux, C, Mitsudomi, T, Peters, S, Rolfo, C, Sacher, A, Senan, S, Ugalde, P & Leighl, NB 2025, 'Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up', Annals of Oncology. https://doi.org/10.1016/j.annonc.2025.08.003

TY - JOUR

T1 - Early and locally advanced non-small-cell lung cancer

T2 - ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

AU - Zer, A.

AU - Ahn, M. J.

AU - Barlesi, F.

AU - Bubendorf, L.

AU - De Ruysscher, D.

AU - Garrido, P.

AU - Gautschi, O.

AU - Hendriks, L. E.

AU - Jänne, P. A.

AU - Kerr, K. M.

AU - Mascaux, C.

AU - Mitsudomi, T.

AU - Peters, S.

AU - Rolfo, C.

AU - Sacher, A.

AU - Senan, S.

AU - Ugalde, P.

AU - Leighl, N. B.

N1 - Publisher Copyright: © 2025 European Society for Medical Oncology. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

PY - 2025

Y1 - 2025

N2 - •This ESMO Clinical Practice Guideline provides key recommendations for managing early and locally advanced NSCLC. •The guideline covers diagnosis, staging, risk assessment, treatment and follow-up. •Treatment algorithms for resectable and unresectable disease are provided. •The authors encompass a multidisciplinary group of experts from different institutions and countries. •Recommendations are based on available scientific data and the authors’ collective expert opinion.

AB - •This ESMO Clinical Practice Guideline provides key recommendations for managing early and locally advanced NSCLC. •The guideline covers diagnosis, staging, risk assessment, treatment and follow-up. •Treatment algorithms for resectable and unresectable disease are provided. •The authors encompass a multidisciplinary group of experts from different institutions and countries. •Recommendations are based on available scientific data and the authors’ collective expert opinion.

KW - diagnosis

KW - early non-small-cell lung cancer (NSCLC)

KW - guideline

KW - staging

KW - treatment

UR - https://www.scopus.com/pages/publications/105018015269

U2 - 10.1016/j.annonc.2025.08.003

DO - 10.1016/j.annonc.2025.08.003

M3 - Article

C2 - 40885528

AN - SCOPUS:105018015269

SN - 0923-7534

JO - Annals of Oncology

JF - Annals of Oncology

ER -

Early and locally advanced non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

Abstract

Keywords

UN SDGs

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