Domino living donor liver transplantation of familial amyloid polyneuropathy patient-A case report-

Background: Familial amyloid polyneuropathy (FAP) is caused by a mutation in a gene tran-scribing transport protein produced mainly by the liver. Liver transplantation is required to stop FAP progression, but the pathology causes anesthetic management challenges. Case: We report a case of domino living donor liver transplantation in a FAP patient. No in-traoperative events occurred; however, during postoperative day 1 in the intensive care unit (ICU), the FAP patient underwent multiple cardiopulmonary resuscitation (CPR) sessions due to pulseless electrical activity following a sudden drop in blood pressure and ventricular tachycardia. Despite ICU management, the patient died after the third CPR session. Conclusions: Various anesthetic management techniques should be considered for FAP pa-tients. Anesthetic management was carefully assessed with the use of isoflurane, iso-proterenol, and an external patch. The cause of deterioration in the ICU is unclear, but further investigation is needed to prevent and better manage postoperative morbidity and mor-tality.