TY - GEN
T1 - DNA hydrogels
AU - Um, Soong Ho
AU - Park, Nokyoung
AU - Luo, Dan
PY - 2006
Y1 - 2006
N2 - DNA hydrogel was constructed by the cross-connection of the branched DNA molecules trough enzymatic catalytic reaction. Three different types of branched DNA, X-, Y-, T-shaped DNA were tested as both building block and crosslinker. Swelling degree and degradation of the DNA hydrogel strongly relied on the initial concentration and types of DNA building blocks: X-DNA gel with highest concentration (0.2 mM) showed the highest swelling degree (approximately 700%) and the strongest resistance to degradation over other hydrogels. DNA hydrogel was explored as new controlled drug delivery, cell encapsulation matrix, and even novel protein production system.
AB - DNA hydrogel was constructed by the cross-connection of the branched DNA molecules trough enzymatic catalytic reaction. Three different types of branched DNA, X-, Y-, T-shaped DNA were tested as both building block and crosslinker. Swelling degree and degradation of the DNA hydrogel strongly relied on the initial concentration and types of DNA building blocks: X-DNA gel with highest concentration (0.2 mM) showed the highest swelling degree (approximately 700%) and the strongest resistance to degradation over other hydrogels. DNA hydrogel was explored as new controlled drug delivery, cell encapsulation matrix, and even novel protein production system.
UR - https://www.scopus.com/pages/publications/40949084030
U2 - 10.1557/proc-0950-d09-03
DO - 10.1557/proc-0950-d09-03
M3 - Conference contribution
AN - SCOPUS:40949084030
SN - 9781604234060
T3 - Materials Research Society Symposium Proceedings
SP - 94
EP - 98
BT - Materials Research Society Symposium Proceedings
PB - Materials Research Society
T2 - 2006 MRS Fall Meeting
Y2 - 27 November 2006 through 1 December 2006
ER -