Direct access to isoindolines through tandem Rh(iii)-catalyzed alkenylation and cyclization of N-benzyltriflamides

Neeraj Kumar Mishra; Jihye Park; Satyasheel Sharma; Sangil Han; Mirim Kim; Youngmi Shin; Jinbong Jang; Jong Hwan Kwak; Young Hoon Jung; In Su Kim

doi:10.1039/c3cc49486a

Direct access to isoindolines through tandem Rh(iii)-catalyzed alkenylation and cyclization of N-benzyltriflamides

Neeraj Kumar Mishra
, Jihye Park
, Satyasheel Sharma
, Sangil Han
, Mirim Kim
, Youngmi Shin
, Jinbong Jang
, Jong Hwan Kwak
, Young Hoon Jung
, In Su Kim

Department of Pharmacy

Sungkyunkwan University

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

The rhodium-catalyzed oxidative alkenylation of N-benzyltriflamides with olefins followed by an intramolecular cyclization via C-H bond activation is described. This method results in the direct and efficient synthesis of highly substituted isoindoline frameworks.

Original language	English
Pages (from-to)	2350-2352
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	18
DOIs	https://doi.org/10.1039/c3cc49486a
State	Published - 4 Feb 2014

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10.1039/c3cc49486a

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title = "Direct access to isoindolines through tandem Rh(iii)-catalyzed alkenylation and cyclization of N-benzyltriflamides",

abstract = "The rhodium-catalyzed oxidative alkenylation of N-benzyltriflamides with olefins followed by an intramolecular cyclization via C-H bond activation is described. This method results in the direct and efficient synthesis of highly substituted isoindoline frameworks.",

author = "Mishra, \{Neeraj Kumar\} and Jihye Park and Satyasheel Sharma and Sangil Han and Mirim Kim and Youngmi Shin and Jinbong Jang and Kwak, \{Jong Hwan\} and Jung, \{Young Hoon\} and Kim, \{In Su\}",

year = "2014",

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doi = "10.1039/c3cc49486a",

language = "English",

volume = "50",

pages = "2350--2352",

journal = "Chemical Communications",

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TY - JOUR

T1 - Direct access to isoindolines through tandem Rh(iii)-catalyzed alkenylation and cyclization of N-benzyltriflamides

AU - Mishra, Neeraj Kumar

AU - Park, Jihye

AU - Sharma, Satyasheel

AU - Han, Sangil

AU - Kim, Mirim

AU - Shin, Youngmi

AU - Jang, Jinbong

AU - Kwak, Jong Hwan

AU - Jung, Young Hoon

AU - Kim, In Su

PY - 2014/2/4

Y1 - 2014/2/4

N2 - The rhodium-catalyzed oxidative alkenylation of N-benzyltriflamides with olefins followed by an intramolecular cyclization via C-H bond activation is described. This method results in the direct and efficient synthesis of highly substituted isoindoline frameworks.

AB - The rhodium-catalyzed oxidative alkenylation of N-benzyltriflamides with olefins followed by an intramolecular cyclization via C-H bond activation is described. This method results in the direct and efficient synthesis of highly substituted isoindoline frameworks.

UR - https://www.scopus.com/pages/publications/84893553445

U2 - 10.1039/c3cc49486a

DO - 10.1039/c3cc49486a

M3 - Article

C2 - 24448389

AN - SCOPUS:84893553445

SN - 1359-7345

VL - 50

SP - 2350

EP - 2352

JO - Chemical Communications

JF - Chemical Communications

IS - 18

ER -

Direct access to isoindolines through tandem Rh(iii)-catalyzed alkenylation and cyclization of N-benzyltriflamides

Abstract

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